TY - JOUR
T1 - Lone-term cognitive impact of anticholinergic medications in older adults
AU - Bottiggi, Kara A.
AU - Salazar, Juan C.
AU - Yu, Lei
AU - Caban-Holt, Allison M.
AU - Ryan, Melody
AU - Mendiondo, Marta S.
AU - Schmitt, Frederick A.
PY - 2006/11
Y1 - 2006/11
N2 - Objective: The objective of this study was to determine whether chronic use of medications with anticholinergic (AC) properties impact older adults' cognitive functioning. Methods: Six years of cognitive test data from two groups of older adults (AC and control) were examined retrospectively (N = 592). Results: Declines over time were found for the AC group on parts A and B of the Trail Making Test. Conclusion: Physicians prescribing ACs to older adult patients should be aware of their potential effects on psychomotor speed and executive functioning. These cognitive effects may lead to impairments in daily functioning resulting in the need to reevaluate patient medications.
AB - Objective: The objective of this study was to determine whether chronic use of medications with anticholinergic (AC) properties impact older adults' cognitive functioning. Methods: Six years of cognitive test data from two groups of older adults (AC and control) were examined retrospectively (N = 592). Results: Declines over time were found for the AC group on parts A and B of the Trail Making Test. Conclusion: Physicians prescribing ACs to older adult patients should be aware of their potential effects on psychomotor speed and executive functioning. These cognitive effects may lead to impairments in daily functioning resulting in the need to reevaluate patient medications.
KW - Anticholinergic
KW - Cognition
KW - Normal aging
KW - Older adults
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U2 - 10.1097/01.JGP.0000224619.87681.71
DO - 10.1097/01.JGP.0000224619.87681.71
M3 - Article
C2 - 17068321
AN - SCOPUS:33750727421
SN - 1064-7481
VL - 14
SP - 980
EP - 984
JO - American Journal of Geriatric Psychiatry
JF - American Journal of Geriatric Psychiatry
IS - 11
ER -
