Long-term mortality and estimated functional capacity among women with symptoms of ischemic heart disease: From the NHLBI-sponsored Women's Ischemia Syndrome Evaluation

Islam Y. Elgendy; Hend Mansoor; Qian Li; Yi Guo; Eileen M. Handberg; C. Noel Bairey Merz; Carl J. Pepine

doi:10.1016/j.ahj.2018.08.010

Long-term mortality and estimated functional capacity among women with symptoms of ischemic heart disease: From the NHLBI-sponsored Women's Ischemia Syndrome Evaluation

Islam Y. Elgendy, Hend Mansoor, Qian Li, Yi Guo, Eileen M. Handberg, C. Noel Bairey Merz, Carl J. Pepine

Pharmacy Practice and Science

Research output: Contribution to journal › Letter › peer-review

4 Scopus citations

Abstract

The aim of this study was to determine the long-term prognostic value of the Duke Activity Status Index–estimated metabolic equivalents (METs) values among women with suspected ischemic heart disease. At a median of 9.6 years, the incidence of death was 23.4% in those with METs <4.8 versus 8.2% in METs >9.9, P <.01. In conclusion, use of the simple, patient-reported Duke Activity Status Index could help identify higher-risk women with suspected ischemic heart disease for targeted risk management.

Original language	English
Pages (from-to)	123-126
Number of pages	4
Journal	American Heart Journal
Volume	206
DOIs	https://doi.org/10.1016/j.ahj.2018.08.010
State	Published - Dec 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Inc.

Funding

This work was supported by contracts from the National Heart, Lung, and Blood Institutes N01-HV-68161-4, U0164829, U01 HL649141, U01 HL649241, K23HL105787, T32HL69751, and R01HL090957; National Institute on Aging 1R03AG032631; and National Center for Research Resources GCRC grant MO1-RR00425; National Center for Advancing Translational Sciences UL1TR000124 and UL1TR001427; and grants from the Gustavus and Louis Pfeiffer Research Foundation, Danville, NJ; The Ladies Hospital Aid Society of Western Pennsylvania, Pittsburgh, PA; and QMED, Inc, Laurence Harbor, NJ; The Society for Women's Health Research (SWHR), Washington, DC; the Edythe L. Broad and the Constance Austin Women's Heart Research Fellowships; the Barbra Streisand Women's Cardiovascular Research and Education Program; The Linda Joy Pollin Women's Heart Health Program; the Erika Glazer Women's Heart Research Initiative; The Women's Guild; and the Adelson Family Foundation, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA; the Gatorade Trust through funds distributed by the University of Florida Department of Medicine, and PCORnet-OneFlorida Clinical Research Consortium CDRN-1501-26692, University of Florida, Gainesville, FL.

Funders	Funder number
National Institute on Aging	1R03AG032631
National Center for Research Resources	MO1-RR00425
National Center for Advancing Translational Sciences (NCATS)	UL1TR000124, UL1TR001427

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.ahj.2018.08.010

Cite this

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title = "Long-term mortality and estimated functional capacity among women with symptoms of ischemic heart disease: From the NHLBI-sponsored Women's Ischemia Syndrome Evaluation",

abstract = "The aim of this study was to determine the long-term prognostic value of the Duke Activity Status Index–estimated metabolic equivalents (METs) values among women with suspected ischemic heart disease. At a median of 9.6 years, the incidence of death was 23.4% in those with METs <4.8 versus 8.2% in METs >9.9, P <.01. In conclusion, use of the simple, patient-reported Duke Activity Status Index could help identify higher-risk women with suspected ischemic heart disease for targeted risk management.",

author = "Elgendy, {Islam Y.} and Hend Mansoor and Qian Li and Yi Guo and Handberg, {Eileen M.} and {Bairey Merz}, {C. Noel} and Pepine, {Carl J.}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2018",

month = dec,

doi = "10.1016/j.ahj.2018.08.010",

language = "English",

volume = "206",

pages = "123--126",

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T1 - Long-term mortality and estimated functional capacity among women with symptoms of ischemic heart disease

T2 - From the NHLBI-sponsored Women's Ischemia Syndrome Evaluation

AU - Elgendy, Islam Y.

AU - Mansoor, Hend

AU - Li, Qian

AU - Guo, Yi

AU - Handberg, Eileen M.

AU - Bairey Merz, C. Noel

AU - Pepine, Carl J.

PY - 2018/12

Y1 - 2018/12

N2 - The aim of this study was to determine the long-term prognostic value of the Duke Activity Status Index–estimated metabolic equivalents (METs) values among women with suspected ischemic heart disease. At a median of 9.6 years, the incidence of death was 23.4% in those with METs <4.8 versus 8.2% in METs >9.9, P <.01. In conclusion, use of the simple, patient-reported Duke Activity Status Index could help identify higher-risk women with suspected ischemic heart disease for targeted risk management.

AB - The aim of this study was to determine the long-term prognostic value of the Duke Activity Status Index–estimated metabolic equivalents (METs) values among women with suspected ischemic heart disease. At a median of 9.6 years, the incidence of death was 23.4% in those with METs <4.8 versus 8.2% in METs >9.9, P <.01. In conclusion, use of the simple, patient-reported Duke Activity Status Index could help identify higher-risk women with suspected ischemic heart disease for targeted risk management.

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M3 - Letter

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AN - SCOPUS:85058014876

SN - 0002-8703

VL - 206

SP - 123

EP - 126

JO - American Heart Journal

JF - American Heart Journal

ER -

Long-term mortality and estimated functional capacity among women with symptoms of ischemic heart disease: From the NHLBI-sponsored Women's Ischemia Syndrome Evaluation

Abstract

Bibliographical note

Funding

ASJC Scopus subject areas

Access to Document

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