Long-term outcome of infrapopliteal catheter-based intervention for critical limb ischemia

Nick N. Abedi, Daniel L. Davenport, Nikolaos Karagiorgos, David J. Minion, Ehab E. Sorial, Eric D. Endean, Eleftherios S. Xenos

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

CONTEXT: Percutaneous treatment of tibioperoneal occlusive disease is associated with decreased morbidity compared with bypass surgery. The long-term patency and limb salvage rates are not well documented. AIMs: To evaluate the long-term outcome of endoluminal interventions for tibioperoneal lesions. METHODS: A retrospective study was performed to determine the outcomes of patients undergoing infrapopliteal catheter-based intervention for critical limb ischemia. Collected data included demographics, comorbidities, clinical presentation, pre- and postintervention noninvasive vascular measurements (segmental pressure and waveforms, and ankle-brachial index [ABI]), type of intervention, limb loss rate, patient follow-up and need for surgical revascularization. Statistical analysis was performed with the two-tailed t test. P<0.05 was considered significant; results were reported as mean ± SD. Cox regression analysis and Kaplan-Meier limb survival analysis were performed to demonstrate freedom from amputation over time. results: Thirty-five patients underwent intervention from 2003 to 2008; technical success was achieved in 26 patients (75%). Arterial segmental pressure studies revealed a significant increase in ABI preprocedure ABI was 0.62±0.24 versus a postintervention ABI of 0.81±0.29 (P=0.02). The limb salvage rate was 63% during the follow-up period. Limb salvage was better for patients who underwent isolated infrapopliteal intervention versus combined above and below the knee intervention. CONCLUSION: Percutaneous interventions for tibioperoneal occlu- sive disease offer an acceptable limb salvage rate and may be the preferred initial treatment for critical limb ischemia.

Original languageEnglish
Pages (from-to)126-128
Number of pages3
JournalInternational Journal of Angiology
Volume18
Issue number3
DOIs
StatePublished - Sep 2009

Keywords

  • Atherectomy
  • Critical limb ischemia
  • Tibioperoneal angioplasty

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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