TY - JOUR
T1 - Long-term outcome of infrapopliteal catheter-based intervention for critical limb ischemia
AU - Abedi, Nick N.
AU - Davenport, Daniel L.
AU - Karagiorgos, Nikolaos
AU - Minion, David J.
AU - Sorial, Ehab E.
AU - Endean, Eric D.
AU - Xenos, Eleftherios S.
PY - 2009/9
Y1 - 2009/9
N2 - CONTEXT: Percutaneous treatment of tibioperoneal occlusive disease is associated with decreased morbidity compared with bypass surgery. The long-term patency and limb salvage rates are not well documented. AIMs: To evaluate the long-term outcome of endoluminal interventions for tibioperoneal lesions. METHODS: A retrospective study was performed to determine the outcomes of patients undergoing infrapopliteal catheter-based intervention for critical limb ischemia. Collected data included demographics, comorbidities, clinical presentation, pre- and postintervention noninvasive vascular measurements (segmental pressure and waveforms, and ankle-brachial index [ABI]), type of intervention, limb loss rate, patient follow-up and need for surgical revascularization. Statistical analysis was performed with the two-tailed t test. P<0.05 was considered significant; results were reported as mean ± SD. Cox regression analysis and Kaplan-Meier limb survival analysis were performed to demonstrate freedom from amputation over time. results: Thirty-five patients underwent intervention from 2003 to 2008; technical success was achieved in 26 patients (75%). Arterial segmental pressure studies revealed a significant increase in ABI preprocedure ABI was 0.62±0.24 versus a postintervention ABI of 0.81±0.29 (P=0.02). The limb salvage rate was 63% during the follow-up period. Limb salvage was better for patients who underwent isolated infrapopliteal intervention versus combined above and below the knee intervention. CONCLUSION: Percutaneous interventions for tibioperoneal occlu- sive disease offer an acceptable limb salvage rate and may be the preferred initial treatment for critical limb ischemia.
AB - CONTEXT: Percutaneous treatment of tibioperoneal occlusive disease is associated with decreased morbidity compared with bypass surgery. The long-term patency and limb salvage rates are not well documented. AIMs: To evaluate the long-term outcome of endoluminal interventions for tibioperoneal lesions. METHODS: A retrospective study was performed to determine the outcomes of patients undergoing infrapopliteal catheter-based intervention for critical limb ischemia. Collected data included demographics, comorbidities, clinical presentation, pre- and postintervention noninvasive vascular measurements (segmental pressure and waveforms, and ankle-brachial index [ABI]), type of intervention, limb loss rate, patient follow-up and need for surgical revascularization. Statistical analysis was performed with the two-tailed t test. P<0.05 was considered significant; results were reported as mean ± SD. Cox regression analysis and Kaplan-Meier limb survival analysis were performed to demonstrate freedom from amputation over time. results: Thirty-five patients underwent intervention from 2003 to 2008; technical success was achieved in 26 patients (75%). Arterial segmental pressure studies revealed a significant increase in ABI preprocedure ABI was 0.62±0.24 versus a postintervention ABI of 0.81±0.29 (P=0.02). The limb salvage rate was 63% during the follow-up period. Limb salvage was better for patients who underwent isolated infrapopliteal intervention versus combined above and below the knee intervention. CONCLUSION: Percutaneous interventions for tibioperoneal occlu- sive disease offer an acceptable limb salvage rate and may be the preferred initial treatment for critical limb ischemia.
KW - Atherectomy
KW - Critical limb ischemia
KW - Tibioperoneal angioplasty
UR - http://www.scopus.com/inward/record.url?scp=80052975924&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052975924&partnerID=8YFLogxK
U2 - 10.1055/s-0031-1278338
DO - 10.1055/s-0031-1278338
M3 - Article
C2 - 22477512
AN - SCOPUS:80052975924
SN - 1061-1711
VL - 18
SP - 126
EP - 128
JO - International Journal of Angiology
JF - International Journal of Angiology
IS - 3
ER -