Low plasma cholesterol levels in suicidal males: A gender- and body mass index-matched case-control study of suicide attempters and nonattempters

Carmen Diaz-Sastre, Enrique Baca-Garcia, Maria M. Perez-Rodriguez, Eloy Garcia-Resa, Antonio Ceverino, Jeronimo Saiz-Ruiz, Maria A. Oquendo, Jose de Leon

Research output: Contribution to journalArticlepeer-review

55 Scopus citations

Abstract

Findings from animal and human studies suggest an association between low cholesterol levels and suicidal behaviors. The purpose of this case-control study was to test whether cholesterol levels in suicide attempters are lower than in controls without suicide attempt history matched by gender, age, and body mass index (BMI). Suicide attempters (n = 177: 68 men and 109 women) and controls (177 blood donors) were assessed. Serum cholesterol levels were significantly lower in suicide attempters than in controls. After gender stratification, the difference remained significant in men, but not in women.

Original languageEnglish
Pages (from-to)901-905
Number of pages5
JournalProgress in Neuro-Psychopharmacology and Biological Psychiatry
Volume31
Issue number4
DOIs
StatePublished - May 9 2007

Bibliographical note

Funding Information:
This article was supported by the National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD), Comunidad de Madrid CAM 08.5/0003/1999, Fondo de Investigacion Sanitaria (FIS) PI060092, Fondo de Investigacion Sanitaria FIS RD06/0011/0016, the Conchita Rabago Foundation, and the Harriet and Esteban Vicente Foundation. Dr. Baca-Garcia is the Lilly Suicide Scholar at Colombia University.

Funding

This article was supported by the National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD), Comunidad de Madrid CAM 08.5/0003/1999, Fondo de Investigacion Sanitaria (FIS) PI060092, Fondo de Investigacion Sanitaria FIS RD06/0011/0016, the Conchita Rabago Foundation, and the Harriet and Esteban Vicente Foundation. Dr. Baca-Garcia is the Lilly Suicide Scholar at Colombia University.

FundersFunder number
Conchita Rabago Foundation
Fondo de Investigacion SanitariaPI060092, FIS RD06/0011/0016
Harriet and Esteban Vicente Foundation
National Alliance for Research on Schizophrenia and Depression
Comunidad de MadridCAM 08.5/0003/1999

    Keywords

    • Aggressiveness
    • Cholesterol
    • Impulsivity
    • Serotonin
    • Suicide

    ASJC Scopus subject areas

    • Pharmacology
    • Biological Psychiatry

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