Abstract
Cancers of the lung and bronchus are the leading cause of cancer deaths in men and women in the United States, and two-thirds of new lung cancer cases are diagnosed in patients over age 65. There are few dedicated clinical trials in the elderly, leading to both undertreatment and overtreatment biases. Even fit older adults experience age-related decline in physiologic reserve, and additional issues of polypharmacy, geriatric syndromes, and inadequate social support are not uncommon, leading to disparities in treatment and survival. This review discusses the challenges in balancing benefits and harms in management of lung cancer in elderly patients.
| Original language | English |
|---|---|
| Pages (from-to) | 563-577 |
| Number of pages | 15 |
| Journal | Clinics in Geriatric Medicine |
| Volume | 33 |
| Issue number | 4 |
| DOIs | |
| State | Published - Nov 2017 |
Bibliographical note
Publisher Copyright:© 2017 Elsevier Inc.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Elderly
- Geriatric assessment
- Immunotherapy
- Lung cancer
- Lung cancer screening
- Stereotactic body radiation therapy
- Surgical resection
- Targeted therapy
ASJC Scopus subject areas
- Geriatrics and Gerontology
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