Lung transplantation in patients with coal workers' pneumoconiosis

Don Hayes, Enrique Diaz-Guzman, Daniel L. Davenport, Joseph B. Zwischenberger, Mehdi Khosravi, Kimberly J. Absher, Charles W. Hoopes

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Hayes D Jr., Diaz-Guzman E, Davenport DL, Zwischenberger JB, Khosravi M, Absher KJ, Hoopes CW. Lung transplantation in patients with coal workers' pneumoconiosis. Abstract: Patients with coal workers' pneumoconiosis (CWP) can develop chronic respiratory failure and require lung transplantation. A retrospective review was performed of the 712 referrals and 143 patients undergoing unilateral or bilateral lung transplantation at the University of Kentucky Medical Center between January 1999 and July 2009. Twenty-one of the 712 referrals (3%) had a diagnosis of CWP with eight patients eventually undergoing lung transplant (six single, two bilateral). The mean age of the cohort was 53±5 (mean±SD) yr (range 45-59). There was no increased risk of perioperative or postoperative complications. Six patients (75%) remain alive after a mean follow-up of 1013±857d with the two deaths attributable to sepsis 683 and 145d after transplant, respectively. There were no pulmonary complications because of the native lung in patients after a single lung transplant, with otherwise good clinical outcomes seen after lung transplantation.

Original languageEnglish
Pages (from-to)629-634
Number of pages6
JournalClinical Transplantation
Volume26
Issue number4
DOIs
StatePublished - Jul 2012

Keywords

  • Black lung
  • Coal miner
  • Coal workers' pneumoconiosis
  • Lung transplantation
  • Progressive massive fibrosis

ASJC Scopus subject areas

  • Transplantation

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