Making of viral replication organelles by remodeling interior membranes

Zsuzsanna Sasvari, Peter D. Nagy

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Positive-stranded RNA (+RNA) viruses exploit host cell machinery by subverting host proteins and membranes and altering cellular pathways during infection. To achieve robust replication, some +RNA viruses, such as poliovirus (PV), build special intracellular compartments, called viral replication organelles. A recent work from the Altan-Bonnett laboratory [1] gave new insights into the formation of poliovirus replication organelles, which are unique subcellular structures containing many individual replication complexes as a result of dynamic cellular membrane remodeling.

Original languageEnglish
Pages (from-to)2436-2442
Number of pages7
Issue number11
StatePublished - Nov 2010


  • Arf1
  • Host factor
  • Membrane remodeling
  • Poliovirus
  • Virus replication

ASJC Scopus subject areas

  • Infectious Diseases
  • Virology


Dive into the research topics of 'Making of viral replication organelles by remodeling interior membranes'. Together they form a unique fingerprint.

Cite this