Management of Ischemic Heart Disease in Patients With Heart Failure: JACC: Heart Failure Position Statement

Lisa M Mielniczuk; Tariq Ahmad; Josip Andelo Borovac; Kemar Brown; Lauren B Cooper; Nadia Fida; Judith S Hochman; Rasha Al Lamee; Jennifer S Lawton; Nikhil Narang; Divaka Perera; Mark C Petrie; Navin Rajagopalan; Nosheen Reza; Peter H Stone; Jacqueline Tamis-Holland; Eric J Velazquez

doi:10.1016/j.jchf.2025.102731

Management of Ischemic Heart Disease in Patients With Heart Failure: JACC: Heart Failure Position Statement

Lisa M Mielniczuk, Tariq Ahmad, Josip Andelo Borovac, Kemar Brown, Lauren B Cooper, Nadia Fida, Judith S Hochman, Rasha Al Lamee, Jennifer S Lawton, Nikhil Narang, Divaka Perera, Mark C Petrie, Navin Rajagopalan, Nosheen Reza, Peter H Stone, Jacqueline Tamis-Holland, Eric J Velazquez

Research output: Contribution to journal › Review article › peer-review

Abstract

Coronary artery disease remains a common cause of morbidity and mortality for patients with heart failure, both in the acute and chronic settings. The management decisions for these patients are complex and are often driven by the clinical setting (ie, acute vs chronic disease) and predominant symptoms (angina vs heart failure). However, there remain significant gaps in the knowledge/evidence around optimal timing and implementation of medical therapy and the role and selection of patients for revascularization. Suggested considerations for clinical practice are provided based on the current body of evidence with emphasis on ongoing gaps in knowledge for future clinical research in this area.

Original language	English
Pages (from-to)	102731
Journal	JACC: Heart Failure
Volume	13
Issue number	12
DOIs	https://doi.org/10.1016/j.jchf.2025.102731
State	Published - Dec 2025

Bibliographical note

Keywords

Humans
Heart Failure/therapy
Myocardial Ischemia/therapy
Myocardial Revascularization/methods
Disease Management

Access to Document

10.1016/j.jchf.2025.102731

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Mielniczuk, L. M., Ahmad, T., Borovac, J. A., Brown, K., Cooper, L. B., Fida, N., Hochman, J. S., Al Lamee, R., Lawton, J. S., Narang, N., Perera, D., Petrie, M. C., Rajagopalan, N., Reza, N., Stone, P. H., Tamis-Holland, J., & Velazquez, E. J. (2025). Management of Ischemic Heart Disease in Patients With Heart Failure: JACC: Heart Failure Position Statement. JACC: Heart Failure, 13(12), 102731. https://doi.org/10.1016/j.jchf.2025.102731

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title = "Management of Ischemic Heart Disease in Patients With Heart Failure: JACC: Heart Failure Position Statement",

abstract = "Coronary artery disease remains a common cause of morbidity and mortality for patients with heart failure, both in the acute and chronic settings. The management decisions for these patients are complex and are often driven by the clinical setting (ie, acute vs chronic disease) and predominant symptoms (angina vs heart failure). However, there remain significant gaps in the knowledge/evidence around optimal timing and implementation of medical therapy and the role and selection of patients for revascularization. Suggested considerations for clinical practice are provided based on the current body of evidence with emphasis on ongoing gaps in knowledge for future clinical research in this area.",

keywords = "Humans, Heart Failure/therapy, Myocardial Ischemia/therapy, Myocardial Revascularization/methods, Disease Management",

author = "Mielniczuk, \{Lisa M\} and Tariq Ahmad and Borovac, \{Josip Andelo\} and Kemar Brown and Cooper, \{Lauren B\} and Nadia Fida and Hochman, \{Judith S\} and \{Al Lamee\}, Rasha and Lawton, \{Jennifer S\} and Nikhil Narang and Divaka Perera and Petrie, \{Mark C\} and Navin Rajagopalan and Nosheen Reza and Stone, \{Peter H\} and Jacqueline Tamis-Holland and Velazquez, \{Eric J\}",

year = "2025",

month = dec,

doi = "10.1016/j.jchf.2025.102731",

language = "English",

volume = "13",

pages = "102731",

number = "12",

}

Mielniczuk, LM, Ahmad, T, Borovac, JA, Brown, K, Cooper, LB, Fida, N, Hochman, JS, Al Lamee, R, Lawton, JS, Narang, N, Perera, D, Petrie, MC, Rajagopalan, N, Reza, N, Stone, PH, Tamis-Holland, J & Velazquez, EJ 2025, 'Management of Ischemic Heart Disease in Patients With Heart Failure: JACC: Heart Failure Position Statement', JACC: Heart Failure, vol. 13, no. 12, pp. 102731. https://doi.org/10.1016/j.jchf.2025.102731

TY - JOUR

T1 - Management of Ischemic Heart Disease in Patients With Heart Failure

T2 - JACC: Heart Failure Position Statement

AU - Mielniczuk, Lisa M

AU - Ahmad, Tariq

AU - Borovac, Josip Andelo

AU - Brown, Kemar

AU - Cooper, Lauren B

AU - Fida, Nadia

AU - Hochman, Judith S

AU - Al Lamee, Rasha

AU - Lawton, Jennifer S

AU - Narang, Nikhil

AU - Perera, Divaka

AU - Petrie, Mark C

AU - Rajagopalan, Navin

AU - Reza, Nosheen

AU - Stone, Peter H

AU - Tamis-Holland, Jacqueline

AU - Velazquez, Eric J

PY - 2025/12

Y1 - 2025/12

N2 - Coronary artery disease remains a common cause of morbidity and mortality for patients with heart failure, both in the acute and chronic settings. The management decisions for these patients are complex and are often driven by the clinical setting (ie, acute vs chronic disease) and predominant symptoms (angina vs heart failure). However, there remain significant gaps in the knowledge/evidence around optimal timing and implementation of medical therapy and the role and selection of patients for revascularization. Suggested considerations for clinical practice are provided based on the current body of evidence with emphasis on ongoing gaps in knowledge for future clinical research in this area.

AB - Coronary artery disease remains a common cause of morbidity and mortality for patients with heart failure, both in the acute and chronic settings. The management decisions for these patients are complex and are often driven by the clinical setting (ie, acute vs chronic disease) and predominant symptoms (angina vs heart failure). However, there remain significant gaps in the knowledge/evidence around optimal timing and implementation of medical therapy and the role and selection of patients for revascularization. Suggested considerations for clinical practice are provided based on the current body of evidence with emphasis on ongoing gaps in knowledge for future clinical research in this area.

KW - Humans

KW - Heart Failure/therapy

KW - Myocardial Ischemia/therapy

KW - Myocardial Revascularization/methods

KW - Disease Management

UR - https://www.scopus.com/pages/publications/105022238314

UR - https://www.scopus.com/inward/citedby.url?scp=105022238314&partnerID=8YFLogxK

U2 - 10.1016/j.jchf.2025.102731

DO - 10.1016/j.jchf.2025.102731

M3 - Review article

C2 - 41338831

SN - 2213-1779

VL - 13

SP - 102731

JO - JACC: Heart Failure

JF - JACC: Heart Failure

IS - 12

ER -

Management of Ischemic Heart Disease in Patients With Heart Failure: JACC: Heart Failure Position Statement

Abstract

Bibliographical note

Keywords

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