Management of Large Aggressive Nonfunctional Pituitary Tumors. Experimental Medical Options When Surgery and Radiation Fail

Brandon A. Miller, W. Caleb Rutledge, Adriana G. Ioachimescu, Nelson M. Oyesiku

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Pituitary adenomas are generally considered benign tumors; however, a subset of these tumors displays aggressive behavior and are not easily cured. The protocol for nonsurgical treatment of aggressive pituitary lesions is less standardized than that of other central nervous system tumors. Aggressive surgical treatment, radiation, dopamine agonists, antiangiogenic drugs, and other chemotherapeutics all have roles in the treatment of aggressive pituitary tumors. More studies are needed to improve outcomes for patients with aggressive pituitary tumors.

Original languageEnglish
Pages (from-to)587-594
Number of pages8
JournalNeurosurgery Clinics of North America
Volume23
Issue number4
DOIs
StatePublished - Oct 2012

Keywords

  • Macroadenoma
  • Nonfunctioning pituitary tumor
  • Pituitary adenoma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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