TY - JOUR
T1 - Marked hypodiploidy in blast phase chronic myelogenous leukemia
T2 - Report of a case and review of the literature
AU - Cibull, Michael L.
AU - Thompson, Mark E.
AU - Smith, Linda
AU - Jennings, C. Darrell
AU - Doukas, Michael A.
AU - Pavlik, Edward J.
AU - Powell, Deborah E.
PY - 1987/3
Y1 - 1987/3
N2 - The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.
AB - The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.
KW - blast phase chronic myelogenous leukemia
KW - cytogenetics
KW - hypodiploidy
UR - http://www.scopus.com/inward/record.url?scp=0023138393&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023138393&partnerID=8YFLogxK
U2 - 10.1002/ajh.2830240309
DO - 10.1002/ajh.2830240309
M3 - Article
C2 - 3469912
AN - SCOPUS:0023138393
SN - 0361-8609
VL - 24
SP - 293
EP - 299
JO - American Journal of Hematology
JF - American Journal of Hematology
IS - 3
ER -