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Maternal Stroke: A Call for Action

  • Islam Y. Elgendy
  • , Syed Bukhari
  • , Amr F. Barakat
  • , Carl J. Pepine
  • , Kathryn J. Lindley
  • , Eliza C. Miller

Research output: Contribution to journalReview articlepeer-review

54 Scopus citations

Abstract

Maternal mortality rates have been steadily increasing in the United States, and cardiovascular mortality is the leading cause of death among pregnant and postpartum women. Maternal stroke accounts for a significant burden of cardiovascular mortality. Data suggest that rates of maternal stroke have been increasing in recent years. Advancing maternal age at the time of birth and the increasing prevalence of traditional cardiovascular risk factors, and other risk factors, as well, such as hypertensive disorders of pregnancy, migraine, and infections, may contribute to increased rates of maternal stroke. In this article, we provide an overview of the epidemiology of maternal stroke, explore mechanisms that may explain increasing rates of stroke among pregnant women, and identify key knowledge gaps for future investigation in this area.

Original languageEnglish
Pages (from-to)727-738
Number of pages12
JournalCirculation
Volume143
Issue number7
DOIs
StatePublished - Feb 16 2021

Bibliographical note

Publisher Copyright:
© 2021 Lippincott Williams and Wilkins. All rights reserved.

Funding

Dr Miller receives funding from the National Institutes of Health, National Institute of Neurological Disorders and Stroke (K23NS107645), and the Louis V. Gerstner Jr Foundation (Gerstner Scholars Program). The other authors have no disclosures.

FundersFunder number
National Institutes of Health (NIH)
Institute of Neurological Disorders and Stroke National Advisory Neurological Disorders and Stroke CouncilK23NS107645

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • cerebral hemorrhage
    • hemorrhagic stroke
    • ischemic stroke
    • postpartum period
    • pre-eclampsia
    • pregnancy
    • subarachnoid hemorrhage

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine
    • Physiology (medical)

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