Mediastinal fibrosis of the pulmonary artery secondary to tuberculosis

Oluseyi Ojeifo, Nisha A. Gilotra, Clinton D. Kemp, Andrew Leventhal, Jon Resar, Kenton J. Zehr, Steve Jones

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Mediastinal fibrosis is an uncommon disease involving the esophagus, respiratory tract, and great vessels. We report a man who presented with dyspnea on exertion. Computed tomography of the chest demonstrated granulomatous disease with dense calcifications leading to severe stenosis of the main pulmonary artery (PA) and narrowing of the superior vena cava. The results of tuberculosis (TB) interferon-γ release assay and TB-polymerase chain reaction were positive for Mycobacterium tuberculosis. The patient received 2 weeks of treatment for latent TB before undergoing resection of fibrotic tissue and replacement of the main and branch PAs using a homograft.

Original languageEnglish
Pages (from-to)e49-e50
JournalAnnals of Thoracic Surgery
Issue number3
StatePublished - Sep 1 2015

Bibliographical note

Publisher Copyright:
© 2015 The Society of Thoracic Surgeons.

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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