Medical Applications of Tissue-Equivalent, Organic-Based Flexible Direct X-Ray Detectors

Laura Basiricò; Andrea Ciavatti; Ilaria Fratelli; Diego Dreossi; Giuliana Tromba; Stefano Lai; Piero Cosseddu; Annalisa Bonfiglio; Francesco Mariotti; Carlo Dalla Val; Valerio Bellucci; John E. Anthony; Beatrice Fraboni

doi:10.3389/fphy.2020.00013

Medical Applications of Tissue-Equivalent, Organic-Based Flexible Direct X-Ray Detectors

Laura Basiricò, Andrea Ciavatti, Ilaria Fratelli, Diego Dreossi, Giuliana Tromba, Stefano Lai, Piero Cosseddu, Annalisa Bonfiglio, Francesco Mariotti, Carlo Dalla Val, Valerio Bellucci, John E. Anthony, Beatrice Fraboni

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

The aim of this study is to assess direct X-ray detectors based on organic thin films, fabricated onto flexible plastic substrates, and operating at ultra-low bias (<1 V), for different medical applications. With this purpose, flexible fully organic pixelated X-ray detectors have been tested at the imaging beamline SYRMEP (SYnchrotron Radiation for MEdical Physics) at the Italian synchrotron Elettra, Trieste. The detectors' performance has been assessed for potential employment both as reliable wearable personal dosimeters for patients and as flexible X-ray medical imaging systems. A spatial resolution of 1.4 lp mm⁻¹ with a contrast of 0.37 has been evaluated. Finally, we validate the detector using X-ray doses and energies typically employed for actual medical radiography, and using X-ray beam pulses provided by a commercial dental radiography system, recording a sensitivity of 1.6 × 10⁵ μC Gy⁻¹ cm⁻³ with a linear response with increasing of the dose rates and a reliable signal to 100 ms X-rays pulses.

Original language	English
Article number	13
Journal	Frontiers in Physics
Volume	8
DOIs	https://doi.org/10.3389/fphy.2020.00013
State	Published - Feb 5 2020

Bibliographical note

Publisher Copyright:
© Copyright © 2020 Basiricò, Ciavatti, Fratelli, Dreossi, Tromba, Lai, Cosseddu, Bonfiglio, Mariotti, Dalla Val, Bellucci, Anthony and Fraboni.

Funding

LB, AC, IF, and BF acknowledge funding from INFN through the CSN5 FIRE project. JA thanks the U.S. National Science Foundation (DMREF-1627428) for support of material synthesis.

Funders	Funder number
National Science Foundation Arctic Social Science Program	DMREF-1627428
National Science Foundation Arctic Social Science Program
Istituto Nazionale di Fisica Nucleare (INFN)

Keywords

flexible electronics
medical dosimetry
organic X-ray detectors
thin films
wearable electronics

ASJC Scopus subject areas

Biophysics
Materials Science (miscellaneous)
Mathematical Physics
General Physics and Astronomy
Physical and Theoretical Chemistry

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10.3389/fphy.2020.00013

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abstract = "The aim of this study is to assess direct X-ray detectors based on organic thin films, fabricated onto flexible plastic substrates, and operating at ultra-low bias (<1 V), for different medical applications. With this purpose, flexible fully organic pixelated X-ray detectors have been tested at the imaging beamline SYRMEP (SYnchrotron Radiation for MEdical Physics) at the Italian synchrotron Elettra, Trieste. The detectors' performance has been assessed for potential employment both as reliable wearable personal dosimeters for patients and as flexible X-ray medical imaging systems. A spatial resolution of 1.4 lp mm−1 with a contrast of 0.37 has been evaluated. Finally, we validate the detector using X-ray doses and energies typically employed for actual medical radiography, and using X-ray beam pulses provided by a commercial dental radiography system, recording a sensitivity of 1.6 × 105 μC Gy−1 cm−3 with a linear response with increasing of the dose rates and a reliable signal to 100 ms X-rays pulses.",

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AU - Tromba, Giuliana

AU - Lai, Stefano

AU - Cosseddu, Piero

AU - Bonfiglio, Annalisa

AU - Mariotti, Francesco

AU - Dalla Val, Carlo

AU - Bellucci, Valerio

AU - Anthony, John E.

AU - Fraboni, Beatrice

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Medical Applications of Tissue-Equivalent, Organic-Based Flexible Direct X-Ray Detectors

Abstract

Bibliographical note

Funding

Keywords

ASJC Scopus subject areas

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