Medullary Thyroid Carcinoma Imaged by Tc-99m MIBI SPECT and TI-201 Chloride/Tc-99m Pertechnetate Subtraction SPECT

Wei Jen Shih, Vickie Stipp, Sylvia Magoun, Kenneth B. Ain, Calixto Pulmano

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A 61-year-old man with medullary thyroid carcinoma and local invasion of the left lobe of the thyroid had Tc-99m MIBI SPECT and TI-201 chloride/Tc-99m pertechnetate subtraction SPECT after left lobectomy of the thyroid, using a triple-headed gamma camera. TI-201 chloride/ Tc-99m pertechnetate subtraction demonstrated a large mass with high TI-201 uptake in the left neck. Although there was intense uptake in the tumor in the left thyroid bed on Tc-99m MIBI neck SPECT, there was also uptake in both salivary glands and the right lobe of the thyroid gland. Thus, uptake in the right lobe of the thyroid gland and the salivary glands might not be differentiated from tumor invasion or metastasis from medullary cell carcinoma. Compared with MIBI SPECT, TI-201 chloride/ Tc-99m pertechnetate subtraction SPECT shows more apparent delineation of tumor uptake and may be a preferable technique.

Original languageEnglish
Pages (from-to)213-217
Number of pages5
JournalClinical Nuclear Medicine
Volume21
Issue number3
DOIs
StatePublished - Mar 1996

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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