Abstract
Balancing biochemical equations for both mass and charge in metabolic networks is critical but unfortunately ignored too often. Failure to do so, for example, results in a common misconception about the origin of protons during lactic fermentation. Lactate, rather than lactic acid, is produced by glycolysis, and its production is a mechanism for alleviating intracellular acidosis due to glycolysis. This error is at the core of some recent papers, and is often ambiguous in biochemistry textbooks.
Original language | English |
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Pages (from-to) | 163-165 |
Number of pages | 3 |
Journal | Metabolomics |
Volume | 5 |
Issue number | 2 |
DOIs | |
State | Published - 2009 |
Bibliographical note
Funding Information:Acknowledgments This work was supported by Kentucky Challenge for Excellence; National Science Foundation/EPSCoR program.
Keywords
- Balanced equation
- Lactic acidosis
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Biochemistry
- Clinical Biochemistry