TY - JOUR
T1 - Metabolic products of microorganisms. 240 urdamycins, new angucycline antibiotics from streptomyces fradiae
T2 - II. Structural studies of urdamycins B to F
AU - Rohr, Jorgen
AU - Zeeck, Axel
PY - 1987
Y1 - 1987
N2 - The structures of the angucycline antibiotics urdamycin B (5), E (2) and F (9) were established by comparing of their spectra with those of urdamycin A (1). The structures of urdamycins C and D, the largest compounds of this series, are still incomplete (10 and 11). The aglycones urdamycinone C, D and E can be liberated by methanolysis of the corresponding urdamycins. The liberation of urdamycinone B (6) requires an alcohol-free medium, to prevent its rearrangement to the naphthacenequinone 7 or 8. The urdamycins differ from other 0-glycoside series in their variety of aglycones.
AB - The structures of the angucycline antibiotics urdamycin B (5), E (2) and F (9) were established by comparing of their spectra with those of urdamycin A (1). The structures of urdamycins C and D, the largest compounds of this series, are still incomplete (10 and 11). The aglycones urdamycinone C, D and E can be liberated by methanolysis of the corresponding urdamycins. The liberation of urdamycinone B (6) requires an alcohol-free medium, to prevent its rearrangement to the naphthacenequinone 7 or 8. The urdamycins differ from other 0-glycoside series in their variety of aglycones.
UR - http://www.scopus.com/inward/record.url?scp=0023267699&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023267699&partnerID=8YFLogxK
U2 - 10.7164/antibiotics.40.459
DO - 10.7164/antibiotics.40.459
M3 - Article
C2 - 3583915
AN - SCOPUS:0023267699
SN - 0021-8820
VL - 40
SP - 459
EP - 467
JO - Journal of Antibiotics
JF - Journal of Antibiotics
IS - 4
ER -