TY - JOUR
T1 - Metal‐Induced Dispersion of Lipid Aggregates
T2 - A Simple, Selective, and Sensitive Fluorescent Metal Ion Sensor
AU - Shnek, Deborah R.
AU - Pack, Daniel W.
AU - Arnold, Frances H.
AU - Sasaki, Darryl Y.
PY - 1995/5/2
Y1 - 1995/5/2
N2 - A new metal ion sensor capable of detecting nanomolar concentrations (< 1 ppb) of Cu2+ is made from mixed vesicles of a novel pyrene‐labeled metal‐chelating ligand and distearoyl phosphatidylcholine. When copper is added, the fluorescence monomer intensity emitted at 377 nm greatly increases, while the intensity of light emitted at 470 nm decreases. This effect is probably due to the dispersal of the fluorescent lipid throughout the matrix upon metal binding and is depicted schematically below. (Figure Presented.)
AB - A new metal ion sensor capable of detecting nanomolar concentrations (< 1 ppb) of Cu2+ is made from mixed vesicles of a novel pyrene‐labeled metal‐chelating ligand and distearoyl phosphatidylcholine. When copper is added, the fluorescence monomer intensity emitted at 377 nm greatly increases, while the intensity of light emitted at 470 nm decreases. This effect is probably due to the dispersal of the fluorescent lipid throughout the matrix upon metal binding and is depicted schematically below. (Figure Presented.)
KW - fluorescent sensors
KW - lipids
KW - metal ion analysis
KW - vesicles
UR - http://www.scopus.com/inward/record.url?scp=33749868543&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749868543&partnerID=8YFLogxK
U2 - 10.1002/anie.199509051
DO - 10.1002/anie.199509051
M3 - Article
AN - SCOPUS:33749868543
SN - 0570-0833
VL - 34
SP - 905
EP - 907
JO - Angewandte Chemie International Edition in English
JF - Angewandte Chemie International Edition in English
IS - 8
ER -