TY - JOUR
T1 - Metastatic breast cancer mimicking hepatocellular carcinoma
T2 - Differences in noninvasive guidelines
AU - Bartram, Anna H.
AU - Villano, John Lee
AU - Ferrera, Dean M.
PY - 2010/6
Y1 - 2010/6
N2 - Hepatocellular carcinoma (HCC), unlike most solid tumors, can be diagnosed noninvasively. We present a case that highlights an important clinical difference between two established guidelines: National Cancer Comprehensive Network (NCCN) and Barcelona-2000 EASL Conference (European Association for the Study of the Liver). Our patient had a large liver mass extending into the right atrium with elevation of the alpha-fetoprotein to 1,130 ng/mL. The radiographic and laboratory evidence is sufficient usingNCCN guidelines to initiate palliative treatment for HCC. The Barcelona-2000 EASL Conference guideline for noninvasive diagnosis is restricted to cirrhotic patients. Our patient did not have a history of chronic liver disease or active hepatitis, and a biopsy was performed that demonstrated breast cancer.
AB - Hepatocellular carcinoma (HCC), unlike most solid tumors, can be diagnosed noninvasively. We present a case that highlights an important clinical difference between two established guidelines: National Cancer Comprehensive Network (NCCN) and Barcelona-2000 EASL Conference (European Association for the Study of the Liver). Our patient had a large liver mass extending into the right atrium with elevation of the alpha-fetoprotein to 1,130 ng/mL. The radiographic and laboratory evidence is sufficient usingNCCN guidelines to initiate palliative treatment for HCC. The Barcelona-2000 EASL Conference guideline for noninvasive diagnosis is restricted to cirrhotic patients. Our patient did not have a history of chronic liver disease or active hepatitis, and a biopsy was performed that demonstrated breast cancer.
KW - AFP
KW - Breast cancer
KW - HCC
KW - Hepatocellular carcinoma
KW - Noninvasive diagnosis
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U2 - 10.1007/s12029-009-9129-0
DO - 10.1007/s12029-009-9129-0
M3 - Article
C2 - 20084472
AN - SCOPUS:77954624935
SN - 1941-6628
VL - 41
SP - 145
EP - 148
JO - Journal of Gastrointestinal Cancer
JF - Journal of Gastrointestinal Cancer
IS - 2
ER -
