Methodological issues in the assessment of neuropsychologic function after cardiac surgery

James A. Blumenthal; Elizabeth P. Mahanna; David J. Madden; William D. White; Narda D. Croughwell; Mark F. Newman

doi:10.1016/0003-4975(95)00055-P

Methodological issues in the assessment of neuropsychologic function after cardiac surgery

James A. Blumenthal, Elizabeth P. Mahanna, David J. Madden, William D. White, Narda D. Croughwell, Mark F. Newman

Anesthesiology

Research output: Contribution to journal › Article › peer-review

113 Scopus citations

Abstract

This report reviews critical issues facing investigators interested in neuropsychologic sequelae after cardiac operations: (1) experimental design; (2) selective attrition; (3) selection of instruments; (4) moderating factors; (5) definitions of cognitive decline; (6) statistical analysis; and (7) clinical significance. Implications for further research in the area are discussed.

Original language	English
Pages (from-to)	1345-1350
Number of pages	6
Journal	Annals of Thoracic Surgery
Volume	59
Issue number	5
DOIs	https://doi.org/10.1016/0003-4975(95)00055-P
State	Published - May 1995

Bibliographical note

Funding Information:
We thank Ms Catherine C. Craver, MEd, for assistance in the preparation of the manuscript. We also thank R. Lloyd Smith, PhD, for statistical advice; Carolina P. Clancy for assistance in neuropsychologic testing; Judy B. Lewis, BSN, and Connie C. Sessions, RN, for assistance in patient recruitment; and Joseph G. Reves, MD. This research was supported by grants, HL49572, AG09663, and MH49679 from the National Institutes of Health.

Funding

We thank Ms Catherine C. Craver, MEd, for assistance in the preparation of the manuscript. We also thank R. Lloyd Smith, PhD, for statistical advice; Carolina P. Clancy for assistance in neuropsychologic testing; Judy B. Lewis, BSN, and Connie C. Sessions, RN, for assistance in patient recruitment; and Joseph G. Reves, MD. This research was supported by grants, HL49572, AG09663, and MH49679 from the National Institutes of Health.

Funders	Funder number
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)	R01HL049572

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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title = "Methodological issues in the assessment of neuropsychologic function after cardiac surgery",

abstract = "This report reviews critical issues facing investigators interested in neuropsychologic sequelae after cardiac operations: (1) experimental design; (2) selective attrition; (3) selection of instruments; (4) moderating factors; (5) definitions of cognitive decline; (6) statistical analysis; and (7) clinical significance. Implications for further research in the area are discussed.",

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AU - Mahanna, Elizabeth P.

AU - Madden, David J.

AU - White, William D.

AU - Croughwell, Narda D.

AU - Newman, Mark F.

N1 - Funding Information: We thank Ms Catherine C. Craver, MEd, for assistance in the preparation of the manuscript. We also thank R. Lloyd Smith, PhD, for statistical advice; Carolina P. Clancy for assistance in neuropsychologic testing; Judy B. Lewis, BSN, and Connie C. Sessions, RN, for assistance in patient recruitment; and Joseph G. Reves, MD. This research was supported by grants, HL49572, AG09663, and MH49679 from the National Institutes of Health.

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N2 - This report reviews critical issues facing investigators interested in neuropsychologic sequelae after cardiac operations: (1) experimental design; (2) selective attrition; (3) selection of instruments; (4) moderating factors; (5) definitions of cognitive decline; (6) statistical analysis; and (7) clinical significance. Implications for further research in the area are discussed.

AB - This report reviews critical issues facing investigators interested in neuropsychologic sequelae after cardiac operations: (1) experimental design; (2) selective attrition; (3) selection of instruments; (4) moderating factors; (5) definitions of cognitive decline; (6) statistical analysis; and (7) clinical significance. Implications for further research in the area are discussed.

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Methodological issues in the assessment of neuropsychologic function after cardiac surgery

Abstract

Bibliographical note

Funding

ASJC Scopus subject areas

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