Abstract
This report reviews critical issues facing investigators interested in neuropsychologic sequelae after cardiac operations: (1) experimental design; (2) selective attrition; (3) selection of instruments; (4) moderating factors; (5) definitions of cognitive decline; (6) statistical analysis; and (7) clinical significance. Implications for further research in the area are discussed.
Original language | English |
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Pages (from-to) | 1345-1350 |
Number of pages | 6 |
Journal | Annals of Thoracic Surgery |
Volume | 59 |
Issue number | 5 |
DOIs | |
State | Published - May 1995 |
Bibliographical note
Funding Information:We thank Ms Catherine C. Craver, MEd, for assistance in the preparation of the manuscript. We also thank R. Lloyd Smith, PhD, for statistical advice; Carolina P. Clancy for assistance in neuropsychologic testing; Judy B. Lewis, BSN, and Connie C. Sessions, RN, for assistance in patient recruitment; and Joseph G. Reves, MD. This research was supported by grants, HL49572, AG09663, and MH49679 from the National Institutes of Health.
ASJC Scopus subject areas
- Surgery
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine