Methylprednisolone preservation of motor nerve function during early degeneration

Edward D. Hall; Daniel L. Wolf

doi:10.1016/0014-4886(84)90219-X

Methylprednisolone preservation of motor nerve function during early degeneration

Edward D. Hall, Daniel L. Wolf

Neuroscience

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Intensive pretreatment of cats with methylprednisolone acetate (8 mg/kg, i.m. once daily for 7 days) was found to significantly preserve the functional capabilities of degenerating soleus motor nerve terminals, as measured at 48 h after motor axon section in the in vivo soleus nerve-muscle preparation. This effect is similar to that reported previously for triamcinolone, another glucocorticoid.

Original language	English
Pages (from-to)	715-720
Number of pages	6
Journal	Experimental Neurology
Volume	84
Issue number	3
DOIs	https://doi.org/10.1016/0014-4886(84)90219-X
State	Published - Jun 1984

ASJC Scopus subject areas

Neurology
Developmental Neuroscience

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title = "Methylprednisolone preservation of motor nerve function during early degeneration",

abstract = "Intensive pretreatment of cats with methylprednisolone acetate (8 mg/kg, i.m. once daily for 7 days) was found to significantly preserve the functional capabilities of degenerating soleus motor nerve terminals, as measured at 48 h after motor axon section in the in vivo soleus nerve-muscle preparation. This effect is similar to that reported previously for triamcinolone, another glucocorticoid.",

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AB - Intensive pretreatment of cats with methylprednisolone acetate (8 mg/kg, i.m. once daily for 7 days) was found to significantly preserve the functional capabilities of degenerating soleus motor nerve terminals, as measured at 48 h after motor axon section in the in vivo soleus nerve-muscle preparation. This effect is similar to that reported previously for triamcinolone, another glucocorticoid.

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Methylprednisolone preservation of motor nerve function during early degeneration

Abstract

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