MicroRNAs: Novel players in cancer diagnosis and therapies

Aaron L. Oom, Brock A. Humphries, Chengfeng Yang

Research output: Contribution to journalReview articlepeer-review

68 Scopus citations

Abstract

First discovered in 1993, microRNAs (miRNAs) have been one of the hottest research areas over the past two decades. Oftentimes, miRNAs levels are found to be dysregulated in cancer patients. The potential use of miRNAs in cancer therapies is an emerging and promising field, with research finding miRNAs to play a role in cancer initiation, tumor growth, and metastasis. Therefore, miRNAs could become an integral part from cancer diagnosis to treatment in future. This review aims to examine current novel research work on the potential roles of miRNAs in cancer therapies, while also discussing several current challenges and needed future research.

Original languageEnglish
Article number959461
JournalBioMed Research International
Volume2014
DOIs
StatePublished - 2014

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology

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