Model of recovery of locomotor ability after sensorimotor cortex injury in rats

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations

Abstract

Animal models of locomotor recovery after brain injury provide tools for understanding the basic neurobiological processes that may underlie recovery after stroke in humans. Measurement of the ability of rats to traverse a narrow elevated beam has proven to be a particularly useful test of locomotor function. Repeated measurement of this behavior over time provides a simple method for quantifying the rate and degree of a rat's locomotor recovery after sensorimotor cortex injury and constitutes a tool for studying its mechanisms and possible treatment strategies. The model has proven particularly useful in predicting the effects of drugs on poststroke recovery in humans.

Original languageEnglish
Pages (from-to)125-129
Number of pages5
JournalILAR Journal
Volume44
Issue number2
DOIs
StatePublished - 2003

Keywords

  • Brain injury
  • Locomotion
  • Rats
  • Recovery
  • Stroke
  • Trauma

ASJC Scopus subject areas

  • General Medicine

Fingerprint

Dive into the research topics of 'Model of recovery of locomotor ability after sensorimotor cortex injury in rats'. Together they form a unique fingerprint.

Cite this