Abstract
Rapid development and deployment of diagnostic testing for COVID-19 have been a key component of the public health response to the pandemic. Out of necessity, academic and other clinical laboratories developed laboratory testing innovations for COVID-19 to meet clinical testing demands. In addition to constraints on local testing supplies and equipment, a rapidly changing regulatory framework created challenges for translational scientists. Illustrative examples of approaches used to develop laboratory tests during the early stages of the COVID-19 pandemic demonstrate effective team science approaches to this challenging clinical care and public health emergency. These experiences and the associated lessons learned are relevant to the development of public health response plans for future pandemics.
| Original language | English |
|---|---|
| Article number | e93 |
| Journal | Journal of Clinical and Translational Science |
| Volume | 5 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2021 |
Bibliographical note
Publisher Copyright:© The Author(s), 2021. Published by Cambridge University Press on behalf of The Association for Clinical and Translational Science.
Funding
Alex Greninger, MD, Ph.D., has received consultant fees from Abbott Molecular and funding from Abbott Laboratories. Acknowledgments. This work was funded in part by the University of Rochester Center for Leading Innovation and Collaboration (CLIC), under Grant U24TR002260. CLIC is the coordinating center for the Clinical and Translational Science Awards (CTSA) Program, funded by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH). This work was also supported in part by the NIH NCATS through Grant Award Numbers: UL1 TR003107 (James, Moran); UL1TR001998 (Moylan); and UL1 TR002319 (Kessler); and the Arkansas Coronavirus Aid Relief and Economic Security (CARES) fund (Moran, Forrest, Boehme, and James). This work is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.
| Funders | Funder number |
|---|---|
| Arkansas Coronavirus Aid Relief and Economic Security | |
| UK-CARES | |
| University of Rochester Center for Leading Innovation and Collaboration | |
| National Institutes of Health (NIH) | |
| Abbott Laboratories | |
| National Center for Advancing Translational Sciences (NCATS) | UL1TR001998, UL1 TR003107, UL1 TR002319 |
| National Center for Advancing Translational Sciences (NCATS) | |
| Climate and Cryosphere | U24TR002260 |
| Climate and Cryosphere |
Keywords
- COVID-19
- Diagnostic tests
- laboratory developed tests
ASJC Scopus subject areas
- General Medicine
