Abstract
A-B-C type triblock copolymers with the different structure(the type of B segment, the chain length of B, C segment, the order of segments) were synthesized and their efficiency as a gene carrier was evaluated by preparing the polyion complex micelles with plasmid-DNA. The triblock copolymers having B segment with a buffering capacity show the high transfection efficiency. But the A-C-B type triblock copolymer does not show the high efficiency.
Original language | English |
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Pages | 5185-5186 |
Number of pages | 2 |
State | Published - 2005 |
Event | 54th SPSJ Symposium on Macromolecules - Yamagata, Japan Duration: Sep 20 2005 → Sep 22 2005 |
Conference
Conference | 54th SPSJ Symposium on Macromolecules |
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Country/Territory | Japan |
City | Yamagata |
Period | 9/20/05 → 9/22/05 |
Keywords
- Ester-amide Exchange
- Gene Carrier
- Polycation
- Polyethylene Glycol
- Triblock Copolymer
ASJC Scopus subject areas
- General Engineering