Monoaminergic influences on temporal patterning of sexual behavior in male rats

David P. Yells; Mark A. Prendergast; Shelton E. Hendricks; Marnie E. Miller

doi:10.1016/0031-9384(95)00130-B

Monoaminergic influences on temporal patterning of sexual behavior in male rats

David P. Yells, Mark A. Prendergast, Shelton E. Hendricks, Marnie E. Miller

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34 Scopus citations

Abstract

We evaluated the effects of the serotonin (5-HT) presynaptic uptake blocker fluoxetine (FLX) and the dopamine (DA)/noradrenaline (NE) releaser amantadine (AMA), separately and in combination, on the temporal patterning of male rat sexual behavior. FLX alone increased intermount-bout intervals, time-outs, grooming time, ejaculation latency, number of mounts per mount bout, and number of mount bouts per ejaculation. AMA alone had the opposite effect on these measures. Additionally, AMA, when given in combination with FLX, completely reversed the FLX-induced deficits in copulatory behavior. We interpret our results as suggesting an interaction between 5-HT and catecholamines in the temporal patterning of male rat copulatorybehavior. Monamines.

Original language	English
Pages (from-to)	847-852
Number of pages	6
Journal	Physiology and Behavior
Volume	58
Issue number	5
DOIs	https://doi.org/10.1016/0031-9384(95)00130-B
State	Published - Nov 1995

Keywords

Copulatory behavior
Ejaculation
Fluoxetine
Grooming
Noradrenaline
Sex

ASJC Scopus subject areas

Experimental and Cognitive Psychology
Behavioral Neuroscience

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10.1016/0031-9384(95)00130-B

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title = "Monoaminergic influences on temporal patterning of sexual behavior in male rats",

abstract = "We evaluated the effects of the serotonin (5-HT) presynaptic uptake blocker fluoxetine (FLX) and the dopamine (DA)/noradrenaline (NE) releaser amantadine (AMA), separately and in combination, on the temporal patterning of male rat sexual behavior. FLX alone increased intermount-bout intervals, time-outs, grooming time, ejaculation latency, number of mounts per mount bout, and number of mount bouts per ejaculation. AMA alone had the opposite effect on these measures. Additionally, AMA, when given in combination with FLX, completely reversed the FLX-induced deficits in copulatory behavior. We interpret our results as suggesting an interaction between 5-HT and catecholamines in the temporal patterning of male rat copulatorybehavior. Monamines.",

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T1 - Monoaminergic influences on temporal patterning of sexual behavior in male rats

AU - Yells, David P.

AU - Prendergast, Mark A.

AU - Hendricks, Shelton E.

AU - Miller, Marnie E.

PY - 1995/11

Y1 - 1995/11

N2 - We evaluated the effects of the serotonin (5-HT) presynaptic uptake blocker fluoxetine (FLX) and the dopamine (DA)/noradrenaline (NE) releaser amantadine (AMA), separately and in combination, on the temporal patterning of male rat sexual behavior. FLX alone increased intermount-bout intervals, time-outs, grooming time, ejaculation latency, number of mounts per mount bout, and number of mount bouts per ejaculation. AMA alone had the opposite effect on these measures. Additionally, AMA, when given in combination with FLX, completely reversed the FLX-induced deficits in copulatory behavior. We interpret our results as suggesting an interaction between 5-HT and catecholamines in the temporal patterning of male rat copulatorybehavior. Monamines.

AB - We evaluated the effects of the serotonin (5-HT) presynaptic uptake blocker fluoxetine (FLX) and the dopamine (DA)/noradrenaline (NE) releaser amantadine (AMA), separately and in combination, on the temporal patterning of male rat sexual behavior. FLX alone increased intermount-bout intervals, time-outs, grooming time, ejaculation latency, number of mounts per mount bout, and number of mount bouts per ejaculation. AMA alone had the opposite effect on these measures. Additionally, AMA, when given in combination with FLX, completely reversed the FLX-induced deficits in copulatory behavior. We interpret our results as suggesting an interaction between 5-HT and catecholamines in the temporal patterning of male rat copulatorybehavior. Monamines.

KW - Copulatory behavior

KW - Ejaculation

KW - Fluoxetine

KW - Grooming

KW - Noradrenaline

KW - Sex

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JO - Physiology and Behavior

JF - Physiology and Behavior

IS - 5

ER -

Monoaminergic influences on temporal patterning of sexual behavior in male rats

Abstract

Keywords

ASJC Scopus subject areas

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