TY - JOUR
T1 - Monte Carlo simulation of the Leksell Gamma Knife®
T2 - I. Source modelling and calculations in homogeneous media
AU - Moskvin, Vadim
AU - DesRosiers, Colleen
AU - Papiez, Lech
AU - Timmerman, Robert
AU - Randall, Marcus
AU - DesRosiers, Paul
PY - 2002/6/21
Y1 - 2002/6/21
N2 - The Monte Carlo code PENELOPE has been used to simulate photon flux from the Leksell Gamma Knife®, a precision method for treating intracranial lesions. Radiation from a single 60Co assembly traversing the collimator system was simulated, and phase space distributions at the output surface of the helmet for photons and electrons were calculated. The characteristics describing the emitted final beam were used to build a two-stage Monte Carlo simulation of irradiation of a target. A dose field inside a standard spherical polystyrene phantom, usually used for Gamma Knife® dosimetry, has been computed and compared with experimental results, with calculations performed by other authors with the use of the EGS4 Monte Carlo code, and data provided by the treatment planning system Gamma Plan®. Good agreement was found between these data and results of simulations in homogeneous media. Owing to this established accuracy, PENELOPE is suitable for simulating problems relevant to stereotactic radiosurgery.
AB - The Monte Carlo code PENELOPE has been used to simulate photon flux from the Leksell Gamma Knife®, a precision method for treating intracranial lesions. Radiation from a single 60Co assembly traversing the collimator system was simulated, and phase space distributions at the output surface of the helmet for photons and electrons were calculated. The characteristics describing the emitted final beam were used to build a two-stage Monte Carlo simulation of irradiation of a target. A dose field inside a standard spherical polystyrene phantom, usually used for Gamma Knife® dosimetry, has been computed and compared with experimental results, with calculations performed by other authors with the use of the EGS4 Monte Carlo code, and data provided by the treatment planning system Gamma Plan®. Good agreement was found between these data and results of simulations in homogeneous media. Owing to this established accuracy, PENELOPE is suitable for simulating problems relevant to stereotactic radiosurgery.
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U2 - 10.1088/0031-9155/47/12/301
DO - 10.1088/0031-9155/47/12/301
M3 - Article
C2 - 12118597
AN - SCOPUS:0037150458
SN - 0031-9155
VL - 47
SP - 1995
EP - 2011
JO - Physics in Medicine and Biology
JF - Physics in Medicine and Biology
IS - 12
ER -