More Chores for TOR: De Novo Ceramide Synthesis

Robert C. Dickson

Research output: Contribution to journalShort surveypeer-review

3 Scopus citations


In this issue of Cell Metabolism, Aronova et al. (2008) show that target of rapamycin complex 2 (TORC2) controls de novo ceramide synthesis in yeast by regulating the activity of ceramide synthase. This work may provide insight into how chemotherapeutic drugs increase de novo ceramide synthesis and promote cell death in humans.

Original languageEnglish
Pages (from-to)99-100
Number of pages2
JournalCell Metabolism
Issue number2
StatePublished - Feb 6 2008

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology


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