Natural history vs. surgery for Meniere's disease

Herbert Silverstein, Eric Smouha, Raleigh Jones

Research output: Contribution to journalArticlepeer-review

181 Scopus citations


Meniere's disease has an episodic course, and certain patients undergo spontaneous remission of their vertigo. A retrospective study of patients treated from 1974 to 1983 was undertaken to evaluate the long-term outcome of patients with Meniere's disease for whom surgery was recommended, comparing those who had a surgical procedure with a similar group of patients who declined surgery. The surgical procedures performed were endolymphatic subarachnoid shunt (ELS), retrolabyrinthine vestibular neurectomy (RVN), middle fossa vestibular neurectomy (MFVN), and transmeatal cochleovestibular neurectomy (CVN). We used a questionnaire, made up according to the 1985 American Academy of Otolaryngology (AAO) criteria, for reporting results for Meniere's disease treatment, and compared patients who were offered surgery but declined (N = 50) with those who underwent surgery (N = 83). The data were analyzed statistically. Initial evaluation, which included air and bone conduction audiometry, speech discrimination, electronystagmography (ENG), frequency of vertigo attacks per month, and disability, showed both groups to be comparable at the outset. Of the nonoperated group 57% had complete control of vertigo at 2 years; 71% had complete control after an average of 8.3 years. After an ELS, 40% of patients had complete control of vertigo after 2 years; 70% had complete control after an average of 8.7 years. After a neurectomy (RVN or CVN), 93% had complete control of vertigo (average followup, 4.4 years). These results indicate statistically that the ELS procedure does not alter the long-term natural course of vertigo control in Meniere's disease, whereas both the RVN and CVN significantly improve the patient's chance of being permanently free of vertigo attacks.

Original languageEnglish
Pages (from-to)6-16
Number of pages11
JournalOtolaryngology - Head and Neck Surgery
Issue number1
StatePublished - Jan 1989

Bibliographical note

Copyright 2016 Elsevier B.V., All rights reserved.

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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