Natural products as tools for neuroscience: Discovery and development of novel agents to treat drug abuse

Research output: Contribution to journalReview articlepeer-review

51 Scopus citations

Abstract

Much of what we know about the neurosciences is the direct result of studying psychoactive natural products. Unfortunately, there are many gaps in our understanding of the basic biological processes that contribute to the etiology of many CNS disorders. The investigation of psychoactive natural products offers an excellent approach to identify novel agents to treat CNS disorders and to find new chemical tools to better elucidate their biological mechanisms. This review will detail recent progress in a program directed toward investigating psychoactive natural products with the goal of treating drug abuse by targeting κopioid receptors.

Original languageEnglish
Pages (from-to)581-587
Number of pages7
JournalJournal of Natural Products
Volume72
Issue number3
DOIs
StatePublished - Mar 27 2009

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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