TY - GEN
T1 - Near-infrared diffuse optical spectroscopies for measurement of deep tissue blood flow, oxygenation and metabolism
AU - Yu, Guoqiang
AU - Shang, Yu
PY - 2011
Y1 - 2011
N2 - Near-infrared (NIR) diffuse correlation spectroscopy (DCS) flowmeter is an emerging technique for measurement of deep tissue blood flow (up to centimeters). NIR spectroscopy (NIRS) can be used for quantification of tissue oxygenation. The combination of DCS tissue-flowmeter and NIRS tissue-oximeter allows for simultaneously quantifying tissue blood flow and oxygenation in deep tissues. A portable DCS flow-oximeter has also been developed for the measurement of relative changes of tissue blood flow and oxygenation. The novel DCS flow-oximeter employs a new design with significantly less cost (1/2), smaller size (1/5), simpler construction and easier operation compared to the hybrid instruments. Application examples in surgical rooms have shown that DCS-based techniques have high sensitivity to detect tissue hemodynamic changes in clinics. It is expected that with more clinical applications, DCS technologies will emerge rapidly as the technique of choice for clinical investigation of diseases and treatment responses.
AB - Near-infrared (NIR) diffuse correlation spectroscopy (DCS) flowmeter is an emerging technique for measurement of deep tissue blood flow (up to centimeters). NIR spectroscopy (NIRS) can be used for quantification of tissue oxygenation. The combination of DCS tissue-flowmeter and NIRS tissue-oximeter allows for simultaneously quantifying tissue blood flow and oxygenation in deep tissues. A portable DCS flow-oximeter has also been developed for the measurement of relative changes of tissue blood flow and oxygenation. The novel DCS flow-oximeter employs a new design with significantly less cost (1/2), smaller size (1/5), simpler construction and easier operation compared to the hybrid instruments. Application examples in surgical rooms have shown that DCS-based techniques have high sensitivity to detect tissue hemodynamic changes in clinics. It is expected that with more clinical applications, DCS technologies will emerge rapidly as the technique of choice for clinical investigation of diseases and treatment responses.
KW - blood flow
KW - carotid endarterectomy
KW - diffuse optical spectroscopy
KW - oxygenation
KW - revascularization
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U2 - 10.1109/FIIW.2011.6476830
DO - 10.1109/FIIW.2011.6476830
M3 - Conference contribution
AN - SCOPUS:84876081721
SN - 9781467358361
T3 - 2011 Future of Instrumentation International Workshop, FIIW 2011 - Proceedings
SP - 52
EP - 55
BT - 2011 Future of Instrumentation International Workshop, FIIW 2011 - Proceedings
Y2 - 7 November 2011 through 8 November 2011
ER -