Nerve and muscle: Basic concepts

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Reflex and voluntary motor activity results from the integration of multiple and continuous stimuli. The hierarchical division of motor behavior reflects its particular goal. Thus, short interneuron arcs in the spinal cord mediate simple reflexes, and complex motor activities involve central processors, such as motor cortex, cerebellum, and basal ganglia. Regardless of complexity, motor activity always involves nerves and muscles as the final pathway for the production of force and movement. This chapter presents the basic aspects of neuromuscular biology: how neural signals initiate the contractile process, and how it is regulated.

Original languageEnglish
Title of host publicationNeuromuscular Disorders in Clinical Practice
Number of pages16
ISBN (Electronic)9781461465676
StatePublished - Nov 1 2013


  • action potential
  • excitation-contraction coupling
  • ion channels
  • Membrane potential
  • motor unit
  • muscle contraction
  • neuromuscular junction
  • neuromuscular transmission
  • sarcolemma
  • sarcomere

ASJC Scopus subject areas

  • Medicine (all)


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