Neurocognitive effects of Moyamoya disease and concomitant epilepsy

Elizabeth R. Wallace, Lisa M. Koehl

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Moyamoya disease (MMD) is a rare degenerative cerebrovascular disorder that leads to recurrent strokes and cerebral hypoperfusion. Seizures are not uncommon in MMD especially following surgical treatment for the disease. Cognitive changes that are largely executive in nature have been documented following MMD and surgical treatment, although research is limited in adults. Methods: The present case report details the comprehensive neurocognitive evaluation of a patient with MMD and concomitant epilepsy. Results: Neurocognitive findings revealed a prominent dysexecutive pattern and atypically poor performance in areas such as visual and verbal memory. The patient reported significant affective symptoms and functional decline. Conclusions: This case offers insight into unique neurocognitive results that may present in adult MMD cases and underscores the importance of interpreting results in the context of neurological comorbidities in this rare disease.

Original languageEnglish
Article number100003
JournalCerebral Circulation - Cognition and Behavior
Volume2
DOIs
StatePublished - Jan 2021

Bibliographical note

Publisher Copyright:
© 2020

Keywords

  • Cognitive
  • Epilepsy
  • Executive function
  • Moyamoya
  • Vascular

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Biological Psychiatry
  • Neurology
  • Clinical Neurology

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