Neuroendocrine Tumors: Current Recommendations for Diagnosis and Surgical Management

Saju Joseph, Yi Zarn Wang, J. Philip Boudreaux, Lowell B. Anthony, Richard Campeau, Daniel Raines, Thomas O'Dorisio, Vay Liang Go, Aaron I. Vinik, Jason Cundiff, Eugene A. Woltering

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations

Abstract

Neuroendocrine tumors (NETs) are rare neoplasms found in diverse locations within the body. These tumors are commonly classified by the primary tumor's location, further subclassified by their differentiation, and finally segregated by their ability to hypersecrete peptides or amines. A number of groups have summarized their recommendations for diagnosis and therapy; however, the rarity of these lesions makes prospective randomized multiinstitutional trials difficult. Thus, these "consensus statements" often remain opinion-based. The authors have collaboratively developed a consensus on the current diagnostic work-up necessary for patients with NETs to help clinicians with this confusing field and followed this with some of the more advanced surgical techniques and considerations that are currently only available in specialty centers to show the evolving management of NETs.

Original languageEnglish
Pages (from-to)205-231
Number of pages27
JournalEndocrinology and Metabolism Clinics of North America
Volume40
Issue number1
DOIs
StatePublished - Mar 2011

Keywords

  • Biochemical markers
  • Chemotherapy
  • Foregut
  • Hindgut
  • Imaging
  • Midgut
  • Neuroendocrine tumors
  • Radiation therapy
  • Surgery
  • Tumor markers

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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