Neurologic complications of congenital heart disease in adults

Sarah A. Goldstein, Larry B. Goldstein

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Congenital heart disease (CHD) is a heterogeneous group of structural abnormalities of the cardiovascular system that are present at birth. Advances in childhood medical and surgical treatment have led to increasing numbers of adults with CHD. Neurological complications of CHD in adults are varied and can include an increased risk of stroke not only related to the underlying congenital defect and its surgical management but also due to atherosclerotic disease associated with advancing age. In addition to cerebrovascular events, CHD in adults is also associated with an increased risk of neurodevelopmental disorders, cognitive impairment, psychiatric disease, and epilepsy. Collaborative multidisciplinary care with contributions from neurologists and cardiologists with expertise in adult CHD is necessary to provide optimal long-term care for this complex and rapidly evolving population.

Original languageEnglish
Title of host publicationHandbook of Clinical Neurology
Number of pages8
StatePublished - Jan 2021

Publication series

NameHandbook of Clinical Neurology
ISSN (Print)0072-9752
ISSN (Electronic)2212-4152

Bibliographical note

Publisher Copyright:
© 2021 Elsevier B.V.


  • Autism
  • Brain hemorrhage
  • Cognition
  • Congenital heart disease
  • Epilepsy
  • Ischemic stroke

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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