Neurological complications of cardiac surgery

David L. McDonagh, Miles Berger, Joseph P. Mathew, Carmelo Graffagnino, Carmelo A. Milano, Mark F. Newman

Research output: Contribution to journalReview articlepeer-review

71 Scopus citations


As increasing numbers of elderly people undergo cardiac surgery, neurologists are frequently called upon to assess patients with neurological complications from the procedure. Some complications mandate acute intervention, whereas others need longer term observation and management. A large amount of published literature exists about these complications and guidance on best practice is constantly changing. Similarly, despite technological advances in surgical intervention and modifications in surgical technique to make cardiac procedures safer, these advances often create new avenues for neurological injury. Accordingly, rapid and precise neurological assessment and therapeutic intervention rests on a solid understanding of the evidence base and procedural variables.

Original languageEnglish
Pages (from-to)490-502
Number of pages13
JournalThe Lancet Neurology
Issue number5
StatePublished - May 2014

Bibliographical note

Funding Information:
This work was funded by the Duke University Department of Anesthesiology and was supported in part by grants HL096978, HL108280, and HL109971 (to JPM) from the National Institutes of Health (Washington, DC, USA). We thank Kathy Gage (Department of Anesthesiology Duke University, NC, USA) for editorial assistance.

Funding Information:
DLM is a consultant for Cephalogics Corporation, LLC. CG receives research funding from Edge Therapeutics, AstraZeneca, Ornim, and Zoll Corporation. The other authors declare that they have no competing interests.

ASJC Scopus subject areas

  • Clinical Neurology


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