Neurological frontal signs and neuropsychological deficits in schizophrenic patients

Manuel J. Cuesta, Victor Peralta, Jose De Leon

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


A higher prevalence of neurological signs (NS) has been described in schizophrenic patients when compared with controls or patients with other mental illnesses. This study, which includes a sample of 66 DSM-IIIR schizophrenics, was designed to assess the relationship between 7 frontal neurologic signs described by Luria and cognitive disturbances measured by an exhaustive neuropsychological battery. There was a statistically significant relationship between the frontal signs and the cognitive deficits (mean shared variance was 22%) which persisted after correcting for the influence of age, education, and duration of illness.

Original languageEnglish
Pages (from-to)15-20
Number of pages6
JournalSchizophrenia Research
Issue number1-2
StatePublished - May 1996

Bibliographical note

Funding Information:
The authors are grateful to Susan Jensen for her help with editing the article. This study was partially supported by a grant from the Government of Navarra (Spain).


  • cognitive deficit
  • neurological sign
  • schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


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