Neuronal mechanism for acute mechanosensitivity in tactile-foraging waterfowl

Eve R. Schneider, Marco Mastrotto, Willem J. Laursen, Vincent P. Schulz, Jena B. Goodman, Owen H. Funk, Patrick G. Gallagher, Elena O. Gracheva, Sviatoslav N. Bagriantsev

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

Relying almost exclusively on their acute sense of touch, tactile-foraging birds can feed in murky water, but the cellular mechanism is unknown. Mechanical stimuli activate specialized cutaneous end organs in the bill, innervated by trigeminal afferents. We report that trigeminal ganglia (TG) of domestic and wild tactile-foraging ducks exhibit numerical expansion of large-diameter mechanoreceptive neurons expressing the mechano-gated ion channel Piezo2. These features are not found in visually foraging birds. Moreover, in the duck, the expansion of mechanoreceptors occurs at the expense of thermosensors. Direct mechanical stimulation of duck TG neurons evokes high-amplitude depolarizing current with a low threshold of activation, high signal amplification gain, and slow kinetics of inactivation. Together, these factors contribute to efficient conversion of light mechanical stimuli into neuronal excitation. Our results reveal an evolutionary strategy to hone tactile perception in vertebrates at the level of primary afferents.

Original languageEnglish
Pages (from-to)14941-14946
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume111
Issue number41
DOIs
StatePublished - Oct 14 2014

Bibliographical note

Publisher Copyright:
© 2014, National Academy of Sciences. All rights reserved.

Keywords

  • Mechanotransduction
  • Piezo2
  • TRPM8
  • TRPV1

ASJC Scopus subject areas

  • General

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