New antibiotic with typical plant anthraquinone structure obtained studying terrestrial and marine Streptomycetes

Hong Xia Cui, Khaled A. Shaaban, Mirko Schiebel, Song Qin, Hartmut Laatsch

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

In our screening for new antibiotics from bacteria, the streptomycete isolate M097 from Jiaozhou Bay in China was found to produce aloesaponarin II (1a) and 1,6-dihydroxy-8-hydroxymethyl-anthraquinone (2). Similarly, a terrestrial streptomycete GW24/1694 produced 1a and its methyl ether, the new compound 1-hydroxy-6-methoxy-8-methyl-anthraquinone (1b). All structures were derived by spectrochemical analysis and by comparison with reference data. The results showed that the marine streptomycete isolate M097 and the terrestrial streptomycete GW24/1694 could be a promising material for studying the biosynthetic pathway of polyketides.

Original languageEnglish
Pages (from-to)419-421
Number of pages3
JournalWorld Journal of Microbiology and Biotechnology
Volume24
Issue number3
DOIs
StatePublished - Mar 2008

Bibliographical note

Funding Information:
Acknowledgment This work was supported by the Key Innovative Project of CAS (KZCXZ-YW-209, KZCXZ-YW-216).

Keywords

  • 1,6-Dihydroxy-8-hydroxymethyl-anthraquinone
  • 1-Hydroxy-6-methoxy-8-methyl-anthraquinone
  • Aloesaponarin II
  • Streptomycetes

ASJC Scopus subject areas

  • Biotechnology
  • Physiology
  • Applied Microbiology and Biotechnology

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