New antibiotic with typical plant anthraquinone structure obtained studying terrestrial and marine Streptomycetes

Hong Xia Cui, Khaled A. Shaaban, Mirko Schiebel, Song Qin, Hartmut Laatsch

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

In our screening for new antibiotics from bacteria, the streptomycete isolate M097 from Jiaozhou Bay in China was found to produce aloesaponarin II (1a) and 1,6-dihydroxy-8-hydroxymethyl-anthraquinone (2). Similarly, a terrestrial streptomycete GW24/1694 produced 1a and its methyl ether, the new compound 1-hydroxy-6-methoxy-8-methyl-anthraquinone (1b). All structures were derived by spectrochemical analysis and by comparison with reference data. The results showed that the marine streptomycete isolate M097 and the terrestrial streptomycete GW24/1694 could be a promising material for studying the biosynthetic pathway of polyketides.

Original languageEnglish
Pages (from-to)419-421
Number of pages3
JournalWorld Journal of Microbiology and Biotechnology
Volume24
Issue number3
DOIs
StatePublished - Mar 2008

Bibliographical note

Funding Information:
Acknowledgment This work was supported by the Key Innovative Project of CAS (KZCXZ-YW-209, KZCXZ-YW-216).

Keywords

  • 1,6-Dihydroxy-8-hydroxymethyl-anthraquinone
  • 1-Hydroxy-6-methoxy-8-methyl-anthraquinone
  • Aloesaponarin II
  • Streptomycetes

ASJC Scopus subject areas

  • Biotechnology
  • Physiology
  • Applied Microbiology and Biotechnology

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