New pharmacologic strategies for acute neuronal injury

Mark S. Luer, Denise H. Rhoney, Melody Hughes, Jimmi Hatton

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


The number of new drugs for treating neurotrauma is rapidly expanding. Emerging theories regarding the mechanisms of secondary neuronal injury provide the scientific basis for evaluating these new agents. Some of the most promising mechanisms for intervention are ionotropic channel antagonism, inhibition of lipid peroxidation, and neurotrophic factor augmentation. Many of these new agents are undergoing clinical trials to establish their roles in therapy.

Original languageEnglish
Pages (from-to)830-848
Number of pages19
Issue number5 I
StatePublished - Sep 1996

ASJC Scopus subject areas

  • Pharmacology (medical)


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