TY - JOUR
T1 - No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample
AU - Vaquero Lorenzo, C.
AU - Baca-Garcia, E.
AU - Diaz Hernandez, M.
AU - Botillo Martin, C.
AU - Perez-Rodriguez, M. M.
AU - Saiz-Gonzalez, M. D.
AU - Fernández, P.
AU - Quintero Gutierrez, F. J.
AU - Saiz-Ruiz, J.
AU - Fernandez Piqueras, J.
AU - Gonzalez De Rivera, J. L.
AU - De Leon, J.
PY - 2007/4/5
Y1 - 2007/4/5
N2 - This study aims to further evaluate the controversial association between the Ser9Gly polymorphism in codon 9 of the D3 dopamine receptor gene (DRD3) and schizophrenia in psychiatric inpatients acutely hospitalized in two general hospitals in Madrid, Spain. The Ser9Gly polymorphism of the DRD3 was examined in 178 schizophrenic patients, 286 patients with other psychiatric diagnoses, and 132 controls recruited. Genotype frequencies were in Hardy-Weinberg equilibrium. No association was found between schizophrenia and the Ser9Gly polymorphism of the D3 dopamine receptor gene.
AB - This study aims to further evaluate the controversial association between the Ser9Gly polymorphism in codon 9 of the D3 dopamine receptor gene (DRD3) and schizophrenia in psychiatric inpatients acutely hospitalized in two general hospitals in Madrid, Spain. The Ser9Gly polymorphism of the DRD3 was examined in 178 schizophrenic patients, 286 patients with other psychiatric diagnoses, and 132 controls recruited. Genotype frequencies were in Hardy-Weinberg equilibrium. No association was found between schizophrenia and the Ser9Gly polymorphism of the D3 dopamine receptor gene.
KW - Association study
KW - DRD3 gene
KW - Genetics
KW - Schizophrenia
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UR - http://www.scopus.com/inward/citedby.url?scp=34247402055&partnerID=8YFLogxK
U2 - 10.1002/ajmg.b.30331
DO - 10.1002/ajmg.b.30331
M3 - Article
C2 - 17171662
AN - SCOPUS:34247402055
SN - 1552-4841
VL - 144
SP - 344
EP - 346
JO - American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics
JF - American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics
IS - 3
ER -