TY - JOUR
T1 - Nodule-specific cysteine-rich peptides negatively regulate nitrogen-fixing symbiosis in a strain-specific manner in medicago truncatul
AU - Wang, Qi
AU - Liu, Jinge
AU - Li, Hua
AU - Yang, Shengming
AU - Körmöczi, Peter
AU - Kereszt, Attila
AU - Zhu, Hongyan
N1 - Publisher Copyright:
© 2018 The American Phytopathological Society .
PY - 2018/2
Y1 - 2018/2
N2 - Medicago truncatula shows a high level of specificity when interacting with its symbiotic partner Sinorhizobium meliloti. This specificity is mainly manifested at the nitrogen-fixing stage of nodule development, such that a particular bacterial strain forms nitrogen-fixing nodules (NodiFix) on one plant genotype but ineffective nodules (NodIFix ) on another. Recent studies have just begun to reveal the underlying molecular mechanisms that control this specificity. The S. meliloti strain A145 induces the formation of Fix nodules on the accession DZA315.16 but Fix nodules on Jemalong A17. A previous study reported that the formation of Fix nodules on Jemalong A17 by S. meliloti A145 was conditioned by a single recessive allele named Mtsym6. Here we demonstrate that the specificity associated with S. meliloti A145 is controlled by multiple genes in M. truncatula, including NFS1 and NFS2 that encode nodule-specific cysteinerich (NCR) peptides. The two NCR peptides acted dominantly to block rather than promote nitrogen fixation by S. meliloti A145. These two NCR peptides are the same ones that negatively regulate nitrogen-fixing symbiosis associated with S. meliloti Rm41.
AB - Medicago truncatula shows a high level of specificity when interacting with its symbiotic partner Sinorhizobium meliloti. This specificity is mainly manifested at the nitrogen-fixing stage of nodule development, such that a particular bacterial strain forms nitrogen-fixing nodules (NodiFix) on one plant genotype but ineffective nodules (NodIFix ) on another. Recent studies have just begun to reveal the underlying molecular mechanisms that control this specificity. The S. meliloti strain A145 induces the formation of Fix nodules on the accession DZA315.16 but Fix nodules on Jemalong A17. A previous study reported that the formation of Fix nodules on Jemalong A17 by S. meliloti A145 was conditioned by a single recessive allele named Mtsym6. Here we demonstrate that the specificity associated with S. meliloti A145 is controlled by multiple genes in M. truncatula, including NFS1 and NFS2 that encode nodule-specific cysteinerich (NCR) peptides. The two NCR peptides acted dominantly to block rather than promote nitrogen fixation by S. meliloti A145. These two NCR peptides are the same ones that negatively regulate nitrogen-fixing symbiosis associated with S. meliloti Rm41.
UR - http://www.scopus.com/inward/record.url?scp=85041341193&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85041341193&partnerID=8YFLogxK
U2 - 10.1094/MPMI-08-17-0207-R
DO - 10.1094/MPMI-08-17-0207-R
M3 - Article
C2 - 28990486
AN - SCOPUS:85041341193
SN - 0894-0282
VL - 31
SP - 240
EP - 248
JO - Molecular Plant-Microbe Interactions
JF - Molecular Plant-Microbe Interactions
IS - 2
ER -