TY - GEN
T1 - Non-linear frequency modulation and phase coupling in ECG during ventricular fibrillation
AU - Patwardhan, Abhijit
AU - Moghe, Sachin
AU - Wang, Ke
AU - Leonelli, Fabio
PY - 1999
Y1 - 1999
N2 - In the present study we quantified the degree of changes in the dominant frequencies during ventricular fibrillation using Wigner transforms. We used auto-bispectra to quantify phase coupling between the different dominant rhythms. Results of 427 trials in 10 dogs showed substantial frequency modulation within ECGs, upto ±14% from the mean dominant frequency. Bispectra were non-zero in more than 99% of the trials (p<0.05) with peaks around the dominant frequencies (8.8 Hz). These results show that during ventricular fibrillation there is substantial frequency modulation of the dominant rhythms and these rhythms are phase coupled. It is possible that the frequency modulation produces quadratic terms which lead to the observed phase coupling. The assessment of degree of frequency modulation and phase coupling may be useful to quantify the degree of organization or of polymorphism.
AB - In the present study we quantified the degree of changes in the dominant frequencies during ventricular fibrillation using Wigner transforms. We used auto-bispectra to quantify phase coupling between the different dominant rhythms. Results of 427 trials in 10 dogs showed substantial frequency modulation within ECGs, upto ±14% from the mean dominant frequency. Bispectra were non-zero in more than 99% of the trials (p<0.05) with peaks around the dominant frequencies (8.8 Hz). These results show that during ventricular fibrillation there is substantial frequency modulation of the dominant rhythms and these rhythms are phase coupled. It is possible that the frequency modulation produces quadratic terms which lead to the observed phase coupling. The assessment of degree of frequency modulation and phase coupling may be useful to quantify the degree of organization or of polymorphism.
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M3 - Conference contribution
AN - SCOPUS:0033356973
SN - 0780356756
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 307
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
T2 - Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
Y2 - 13 October 1999 through 16 October 1999
ER -