Nonopioid management of acute pain associated with trauma: Focus on pharmacologic options

In conclusion, a number of adjuvant therapies have shown promise in the acute setting of traumatic pain management, and the impact of incorporating multimodal analgesia with multiple categories of nonopioid medications and treatment approaches should be the subject of additional investigation. While these therapies each have specific limitations, it is clearly important to consider early use of multiple nonopioid adjunctive agents early in the treatment of acute traumatic pain. Doing so may decrease opioid requirements and potentially obviate the need for opioids altogether in a population potentially at high risk for dependence, and a goal of discharging a patient on nonopioid analgesics may be attainable.