Abstract
Nonrenal complications of contrast media are caused by chemotoxic or anaphylactoid reactions related to the contrast agent used. Chemotoxicity is mainly attributed to ionic concentration and osmolality. Anaphylactoid reactions are typically caused by direct activation of basophils, mast cells, and complement rather than an observable antigen-antibody interaction, and may be acute or delayed. History of an adverse reaction following prior exposure is the strongest predictor of a subsequent adverse reaction to contrast. Premedication regimens of corticosteroids or antihistamines can lower the risk of repeat adverse reactions. Treatment of anaphylactoid reactions depends on the severity of symptoms.
Original language | English |
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Pages (from-to) | 341-348 |
Number of pages | 8 |
Journal | Interventional Cardiology Clinics |
Volume | 3 |
Issue number | 3 |
DOIs | |
State | Published - Jul 2014 |
Keywords
- Anaphylactoid reactions
- Chemotoxicity
- Contrast media
- Preoperative treatment
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine