Nonrenal Complications of Contrast Media

Damien Marycz, Khaled M. Ziada

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Nonrenal complications of contrast media are caused by chemotoxic or anaphylactoid reactions related to the contrast agent used. Chemotoxicity is mainly attributed to ionic concentration and osmolality. Anaphylactoid reactions are typically caused by direct activation of basophils, mast cells, and complement rather than an observable antigen-antibody interaction, and may be acute or delayed. History of an adverse reaction following prior exposure is the strongest predictor of a subsequent adverse reaction to contrast. Premedication regimens of corticosteroids or antihistamines can lower the risk of repeat adverse reactions. Treatment of anaphylactoid reactions depends on the severity of symptoms.

Original languageEnglish
Pages (from-to)341-348
Number of pages8
JournalInterventional Cardiology Clinics
Volume3
Issue number3
DOIs
StatePublished - Jul 2014

Keywords

  • Anaphylactoid reactions
  • Chemotoxicity
  • Contrast media
  • Preoperative treatment

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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