Novel risk factors for stroke: Homocysteine, inflammation, and infection

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Recent studies have suggested that the risk of stroke may be increased in patients with several novel predisposing conditions. Although some controversy remains, the evidence supporting an association between moderately elevated levels of homocysteine and stroke is fairly strong. Studies are in progress to determine whether treatment with folate in combination with vitamins B6 and B12 will reduce the risk of stroke in patients with increased serum homocysteine. Evidence is also being gathered that suggests that patients with chronic inflammation, as well as those with chronic or acute infection, are at elevated stroke risk. The therapeutic implications of these latter associations have not yet been explored.

Original languageEnglish
Pages (from-to)110-114
Number of pages5
JournalCurrent Atherosclerosis Reports
Issue number2
StatePublished - Mar 2000

Bibliographical note

Publisher Copyright:
© 2000, Current Science Inc.


  • Azithromycin
  • Homocysteine
  • Homocysteine Level
  • Ischemic Stroke
  • Plasma Homocysteine

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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