Novel small molecule growth inhibitor affecting bacterial outer membrane reduces extraintestinal pathogenic escherichia coli (ExPEC) infection in avian model

Immunology and Microbiology

• Extraintestinal Pathogenic Escherichia Coli 100%
• Growth Inhibitor 100%
• Bacterial Outer Membrane 100%
• Aves 100%
• Infection 100%
• Avian Pathogenic Escherichia Coli 94%
• Outer Membrane 11%
• Gram-Negative Bacteria 5%
• Body Weight 5%
• Escherichia coli 5%
• Low Drug Dose 5%
• Lactobacillus 5%
• Urinary Tract 5%
• Uropathogenic Escherichia Coli 5%
• Cecum 5%
• Genetic Similarity 5%
• Essential Gene 5%
• Meningitis 5%
• Pharmacokinetics 5%
• Membrane Permeability 5%
• Antibiotic Resistance 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Escherichia Coli Infection 100%
• Growth Inhibitor 100%
• Extraintestinal Pathogenic Escherichia Coli 100%
• Aves 100%
• Avian Pathogenic Escherichia Coli 70%
• Avian Colibacillosis 23%
• Lipopolysaccharide 17%
• Antiinfective Agent 11%
• Meningitis 11%
• Gram Negative Bacterium 5%
• Antibiotic Therapy 5%
• Antibacterial Therapy 5%
• Infection 5%
• Escherichia coli 5%
• Lead Compound 5%
• Carrier Protein 5%
• Sulfadimethoxine 5%
• Lactobacillus 5%
• Uropathogenic Escherichia Coli 5%
• Urinary Tract Infection 5%
• Oleic Acid 5%
• Pharmacokinetics 5%
• Antibiotic Resistance 5%
• Antibacterial Mechanism 5%