Numerical simulation of the microwave rewarming process of cryopreserved organs

X. Han, D. Y. Gao, D. Luo, C. Yu, C. C. Lu

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

The rewarming process of cryopreserved organs using microwave technology is analyzed by numerical simulation. The FDTD finite-difference time-domain) method is applied to calculate the electromagnetic field in a real microwave rewarming system, composed by a cylindrical resonant cavity, an antenna source, and a frozen rabbit-kidney phantom with temperature-dependent properties. The efficiency of the FDTD codes is improved by nonuniform grid techniques and parallel algorithms. Meanwhile, an apparent specific-heat method is introduced in the temperature-field calculation. Coupling the solutions of the two fields is realized by a formerly developed algorithm. The numerical results show that in the rewarming process of the rabbit kidney phantom, the warming rate can reach 300°-500°C/min, which may prevent devitrification, but the maximum temperature difference in the sample (18 mm in radius) can reach 15°C at the end, which may cause severe thermal stress.

Original languageEnglish
Pages (from-to)201-205
Number of pages5
JournalMicrowave and Optical Technology Letters
Volume46
Issue number3
DOIs
StatePublished - Aug 5 2005

Keywords

  • FDTD
  • Microwave heating
  • Organ cryopreservation
  • Parallel algorithm

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Condensed Matter Physics
  • Electrical and Electronic Engineering

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