Abstract
This study compares the Neurobiologic Risk Score (NBRS) with developmental outcome in 199 infants ⩽1500 g birth weight to determine levels of risk and to investigate the relative contributions of the NBRS and nonmedical factors to developmental outcome. The NBRS correlated significantly (p <.0001) with the Bayley Mental (MOl) and Psychomotor (POI) Indexes, and neurologic examination score (NS) at 6, 15, and 24 months. Three risk groups were identified: Low, NBRS ⩽4; intermediate, NBRS 5 to 7; and high, NBRS ⩾8 with an incidence of major handicaps at 24 months of 7%, 32%, and 50%, respectively. Of eight factors considered, the NBRS accounted for the greatest variance: MOl, 14 to 27%; POI, 25 to 29%; NS, 34 to 42%. Additional increments of variance were contributed by gender (MOl, POI, NS), maternal intelligence and race (MOl), and maternal education (POI). The NBRS is a useful tool for identifying risk for developmental abnormalities due to neonatal medical events.
Original language | English |
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Pages (from-to) | 375-380 |
Number of pages | 6 |
Journal | Journal of Developmental and Behavioral Pediatrics |
Volume | 14 |
Issue number | 6 |
State | Published - Dec 1993 |
Keywords
- Biologic risk
- Developmental follow-up
- Developmental outcome
- Prematurity
- Very low birth weight infants
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Developmental and Educational Psychology
- Psychiatry and Mental health