TY - JOUR
T1 - Nutritional support and growth in thalassaemia major
AU - Fuchs, G. J.
AU - Tienboon, P.
AU - Khaled, M. A.
AU - Nimsakul, S.
AU - Linpisarn, S.
AU - Faruque, A. S.G.
AU - Yutrabootr, Y.
AU - Dewier, M.
AU - Suskind, R. M.
PY - 1997
Y1 - 1997
N2 - Twelve thalassaemic children under 3 years of age received intensive nutritional support for one month and were discharged on a prescribed diet of locally available foods. Anthropometry, bioelectrical impedance analysis and dietary intake were longitudinally assessed. Mean energy intake was 20% greater than the recommended daily allowance during nutritional supplementation as compared with below the recommended daily allowance before and after the period of nutritional support. Weight, but not height, significantly increased during the support period and was due to increases in both fat free mass and fat mass. Body weight, fat free mass and fat mass declined in line with the reduced intake upon return home; however, height velocity accelerated and exceeded normal through the fourth month before resuming a below normal rate. It can be concluded that (1) nutritional stunting as the result of reduced nutrient intake is an important cause of growth failure in young children with thalassaemia and is responsive to nutritional support, (2) the deficit in height velocity was due to retarded truncal height growth, and (3) the bioelectrical impedance analysis method is suitable for body composition analysis of thalassaemic children.
AB - Twelve thalassaemic children under 3 years of age received intensive nutritional support for one month and were discharged on a prescribed diet of locally available foods. Anthropometry, bioelectrical impedance analysis and dietary intake were longitudinally assessed. Mean energy intake was 20% greater than the recommended daily allowance during nutritional supplementation as compared with below the recommended daily allowance before and after the period of nutritional support. Weight, but not height, significantly increased during the support period and was due to increases in both fat free mass and fat mass. Body weight, fat free mass and fat mass declined in line with the reduced intake upon return home; however, height velocity accelerated and exceeded normal through the fourth month before resuming a below normal rate. It can be concluded that (1) nutritional stunting as the result of reduced nutrient intake is an important cause of growth failure in young children with thalassaemia and is responsive to nutritional support, (2) the deficit in height velocity was due to retarded truncal height growth, and (3) the bioelectrical impedance analysis method is suitable for body composition analysis of thalassaemic children.
KW - Anthropometry
KW - Bioimpedance
KW - Malnutrition
KW - Thalassaemia
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U2 - 10.1136/adc.76.6.509
DO - 10.1136/adc.76.6.509
M3 - Article
C2 - 9245848
AN - SCOPUS:0030842072
SN - 0003-9888
VL - 76
SP - 509
EP - 512
JO - Archives of Disease in Childhood
JF - Archives of Disease in Childhood
IS - 6
ER -