Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

Robert N. Helsley; Venkateshwari Varadharajan; Amanda L. Brown; Anthony D. Gromovsky; Rebecca C. Schugar; Iyappan Ramachandiran; Kevin Fung; Mohammad Nasser Kabbany; Rakhee Banerjee; Chase K. Neumann; Chelsea Finney; Preeti Pathak; Danny Orabi; Lucas J. Osborn; William Massey; Renliang Zhang; Anagha Kadam; Brian E. Sansbury; Calvin Pan; Jessica Sacks; Richard G. Lee; Rosanne M. Crooke; Mark J. Graham; Madeleine E. Lemieux; Valentin Gogonea; John P. Kirwan; Daniela S. Allende; Mete Civelek; Paul L. Fox; Lawrence L. Rudel; Aldons J. Lusis; Matthew Spite; J. Mark Brown

doi:10.7554/eLife.49882

Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

Robert N. Helsley, Venkateshwari Varadharajan, Amanda L. Brown, Anthony D. Gromovsky, Rebecca C. Schugar, Iyappan Ramachandiran, Kevin Fung, Mohammad Nasser Kabbany, Rakhee Banerjee, Chase K. Neumann, Chelsea Finney, Preeti Pathak, Danny Orabi, Lucas J. Osborn, William Massey, Renliang Zhang, Anagha Kadam, Brian E. Sansbury, Calvin Pan, Jessica SacksRichard G. Lee, Rosanne M. Crooke, Mark J. Graham, Madeleine E. Lemieux, Valentin Gogonea, John P. Kirwan, Daniela S. Allende, Mete Civelek, Paul L. Fox, Lawrence L. Rudel, Aldons J. Lusis, Matthew Spite, J. Mark Brown

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Original language	English
Journal	eLife
Volume	8
DOIs	https://doi.org/10.7554/eLife.49882
State	Published - Oct 17 2019

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10.7554/eLife.49882

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Helsley, R. N., Varadharajan, V., Brown, A. L., Gromovsky, A. D., Schugar, R. C., Ramachandiran, I., Fung, K., Kabbany, M. N., Banerjee, R., Neumann, C. K., Finney, C., Pathak, P., Orabi, D., Osborn, L. J., Massey, W., Zhang, R., Kadam, A., Sansbury, B. E., Pan, C., ... Brown, J. M. (2019). Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease. eLife, 8. https://doi.org/10.7554/eLife.49882

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title = "Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease",

author = "Helsley, {Robert N.} and Venkateshwari Varadharajan and Brown, {Amanda L.} and Gromovsky, {Anthony D.} and Schugar, {Rebecca C.} and Iyappan Ramachandiran and Kevin Fung and Kabbany, {Mohammad Nasser} and Rakhee Banerjee and Neumann, {Chase K.} and Chelsea Finney and Preeti Pathak and Danny Orabi and Osborn, {Lucas J.} and William Massey and Renliang Zhang and Anagha Kadam and Sansbury, {Brian E.} and Calvin Pan and Jessica Sacks and Lee, {Richard G.} and Crooke, {Rosanne M.} and Graham, {Mark J.} and Lemieux, {Madeleine E.} and Valentin Gogonea and Kirwan, {John P.} and Allende, {Daniela S.} and Mete Civelek and Fox, {Paul L.} and Rudel, {Lawrence L.} and Lusis, {Aldons J.} and Matthew Spite and Brown, {J. Mark}",

year = "2019",

month = oct,

day = "17",

doi = "10.7554/eLife.49882",

language = "English",

volume = "8",

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Helsley, RN, Varadharajan, V, Brown, AL, Gromovsky, AD, Schugar, RC, Ramachandiran, I, Fung, K, Kabbany, MN, Banerjee, R, Neumann, CK, Finney, C, Pathak, P, Orabi, D, Osborn, LJ, Massey, W, Zhang, R, Kadam, A, Sansbury, BE, Pan, C, Sacks, J, Lee, RG, Crooke, RM, Graham, MJ, Lemieux, ME, Gogonea, V, Kirwan, JP, Allende, DS, Civelek, M, Fox, PL, Rudel, LL, Lusis, AJ, Spite, M & Brown, JM 2019, 'Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease', eLife, vol. 8. https://doi.org/10.7554/eLife.49882

TY - JOUR

T1 - Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

AU - Helsley, Robert N.

AU - Varadharajan, Venkateshwari

AU - Brown, Amanda L.

AU - Gromovsky, Anthony D.

AU - Schugar, Rebecca C.

AU - Ramachandiran, Iyappan

AU - Fung, Kevin

AU - Kabbany, Mohammad Nasser

AU - Banerjee, Rakhee

AU - Neumann, Chase K.

AU - Finney, Chelsea

AU - Pathak, Preeti

AU - Orabi, Danny

AU - Osborn, Lucas J.

AU - Massey, William

AU - Zhang, Renliang

AU - Kadam, Anagha

AU - Sansbury, Brian E.

AU - Pan, Calvin

AU - Sacks, Jessica

AU - Lee, Richard G.

AU - Crooke, Rosanne M.

AU - Graham, Mark J.

AU - Lemieux, Madeleine E.

AU - Gogonea, Valentin

AU - Kirwan, John P.

AU - Allende, Daniela S.

AU - Civelek, Mete

AU - Fox, Paul L.

AU - Rudel, Lawrence L.

AU - Lusis, Aldons J.

AU - Spite, Matthew

AU - Brown, J. Mark

PY - 2019/10/17

Y1 - 2019/10/17

U2 - 10.7554/eLife.49882

DO - 10.7554/eLife.49882

M3 - Article

SN - 2050-084X

VL - 8

JO - eLife

JF - eLife

ER -

Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

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